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Efinaconazole in Onychomycosis.

Author: GuptaAditya K, TalukderMesbah

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Efinaconazole 10% topical solution is an effective and safe treatment for onychomycosis, a fungal nail infection, in adults and children. It is recommended as first-line treatment for mild-to-moderate cases.
Paper Details　
Original Abstract of the Article :
Onychomycosis is a fungal nail infection that causes nail discoloration, nail plate thickening, and onycholysis. Efinaconazole 10% topical solution is an FDA-approved treatment for onychomycosis patients aged 6 years and above. The drug functions as an antifungal by disrupting ergosterol synthesis i...See full text at original site
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引用元：
https://doi.org/10.1007/s40257-021-00660-1

データ提供：米国国立医学図書館（NLM）

Efinaconazole: A Novel Treatment for Onychomycosis

This research focuses on the effectiveness of efinaconazole 10% topical solution as a treatment for onychomycosis, a fungal nail infection. Efinaconazole is a potent antifungal agent that disrupts the synthesis of ergosterol, a crucial component of fungal cell membranes. The research highlights its enhanced nail penetration compared to other topical antifungals, making it a promising treatment option for onychomycosis.

Efinaconazole: A Promising First-Line Treatment

The research suggests that efinaconazole 10% topical solution is a safe and effective treatment for onychomycosis, particularly in cases of mild-to-moderate infection, pediatric onychomycosis, and individuals with liver or kidney disease. It also shows promise as maintenance therapy to prevent relapse. The study identified certain patient characteristics that are more likely to respond to efinaconazole, including female patients, those with lower BMI, and those with a shorter disease duration.

Navigating Treatment Options for Onychomycosis

This research provides valuable insights for patients seeking treatment for onychomycosis. Efinaconazole appears to be a promising first-line treatment option, with a favorable safety profile and a high rate of mycological and clinical cure. However, it's essential to consult with a healthcare professional for personalized recommendations based on individual factors, such as disease severity and medical history. Just like a camel adapts its route through the desert based on the terrain, patients should work with their healthcare providers to navigate the best treatment path for their specific needs.

Dr.Camel's Conclusion

This research illuminates the importance of ongoing research and development in the field of fungal infections, particularly those affecting the nail bed. Like a seasoned camel seeking the best water source in the desert, healthcare providers must stay updated on the latest treatments and make informed decisions about the most effective solutions for their patients.

Date :
  1. Date Completed 2022-03-14
  2. Date Revised 2022-03-14
Further Info :

Pubmed ID

34902110

DOI: Digital Object Identifier

10.1007/s40257-021-00660-1

SNS
PICO Info
in preparation
Languages

English

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