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Development of an Innovative Berberine Food-Grade Formulation with an Ameliorated Absorption: In Vitro Evidence Confirmed by Healthy Human Volunteers Pharmacokinetic Study.
Author: AllegriniPietro, ArnoldiLolita, CortiFabrizio, PetrangoliniGiovanna, RivaAntonella, RonchiMassimo
Original Abstract of the Article :
OBJECTIVE: To evaluate in vitro solubility, bioaccessibility, and cytotoxic profile, together with a pharmacokinetic profile by oral administration to healthy volunteers of a novel food-grade berberine formulation (BBR-PP, i.e., berberine Phytosome®). RESULTS: An in vitro increase of solubility in ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8665891/
データ提供:米国国立医学図書館(NLM)
Improving Berberine Absorption: A New Frontier in Metabolic Health
In the realm of metabolic health, researchers are constantly searching for innovative ways to improve the absorption of beneficial compounds. This study delves into the potential of a novel food-grade berberine formulation, known as BBR-PP, to enhance berberine absorption in the body. The study employed a combination of in vitro and human volunteer pharmacokinetic studies to assess the effectiveness of BBR-PP. This research serves as a beacon, illuminating the path toward more efficient and effective delivery of berberine for potential therapeutic applications.
BBR-PP: A Game-Changer for Berberine Absorption
This research revealed that BBR-PP significantly enhanced berberine absorption compared to unformulated berberine, achieving a remarkable 10-fold increase in bioavailability. This groundbreaking discovery has the potential to revolutionize the way we utilize berberine, a naturally occurring compound known for its potential metabolic benefits.
Unlocking the Power of Berberine: A New Era in Metabolic Management
The enhanced bioavailability of berberine through BBR-PP suggests a promising path towards optimizing its therapeutic potential in metabolic discomforts. Imagine a future where this naturally occurring compound can be harnessed more effectively, leading to improved metabolic health.
Dr. Camel's Conclusion
The findings of this study hold immense promise for the future of metabolic health. The novel food-grade berberine formulation, BBR-PP, demonstrates a significant improvement in berberine absorption, opening up new avenues for utilizing this natural compound to address metabolic discomforts. Just like a camel can navigate vast deserts, this discovery offers a promising path toward improving metabolic health.
Date :
- Date Completed n.d.
- Date Revised 2022-04-29
Further Info :
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