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Adverse reactions associated with pentamidine isethionate in AIDS patients: recommendations for monitoring therapy.

Author: AndersenR, BoedickerM, GoldsteinE J, MaM

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Pentamidine was used to treat 24 patients with Pneumocystis carinii pneumonia (PCP). Eighty-three percent of patients experienced adverse effects, including hepatic abnormalities (58%), nausea and vomiting (46%), hypoglycemia (33%), azotemia (25%), and pain at the injection site (25%).
Paper Details　
Original Abstract of the Article :
Since pentamidine has become commercially available, there is renewed interest in using it as the initial treatment for Pneumocystis carinii pneumonia (PCP) in AIDS patients. We reviewed the use of pentamidine in 24 patients with PCP to gain information on the prevalence and severity of adverse effe...See full text at original site
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引用元：
https://doi.org/10.1177/106002808602001108

データ提供：米国国立医学図書館（NLM）

Pentamidine Isethionate: A Double-Edged Sword in the Desert of AIDS

Pentamidine isethionate, a medication used to treat Pneumocystis carinii pneumonia (PCP), a serious lung infection in people with AIDS, has become a vital tool in the fight against this devastating disease. However, this research highlights the potential side effects of pentamidine, urging clinicians to monitor patients closely to ensure safe and effective treatment.

The researchers reviewed the use of pentamidine in 24 patients with PCP. They found that a significant proportion of patients (83%) experienced adverse effects, including liver problems, nausea, vomiting, low blood sugar, kidney problems, and pain at the injection site.

Navigating the Desert of Side Effects: A Cautious Approach

The study emphasizes the importance of careful monitoring during pentamidine therapy, much like a desert traveler must constantly check their supplies.

A Double-Edged Sword in the Fight Against AIDS: Pentamidine

While pentamidine is a powerful tool in the fight against PCP, it’s crucial to be aware of its potential side effects. Close monitoring and early detection of complications are essential to ensure the safety and effectiveness of this medication.

Dr.Camel's Conclusion

Pentamidine, like a precious oasis in the desert of AIDS, can provide life-saving relief. However, it's important to be vigilant for potential side effects and work closely with healthcare providers to navigate this challenging journey.

Date :
  1. Date Completed 1987-01-22
  2. Date Revised 2019-09-12
Further Info :

Pubmed ID

3490958

DOI: Digital Object Identifier

10.1177/106002808602001108

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Article Analysis
・Side Effects of pentamidine injection
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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