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<i>Lactobacillus rhamnosus</i> R0011 Treatment Enhanced Efficacy of Capecitabine against Colon Cancer in Male Balb/c Mice.
Author: AlemrajabiMahdi, AshabiGhorbangol, HalimiShahnaz, NabavizadehFatemeh, PanahiMahshid, RahimiAhmad Mustafa, RahimpourMilad
Original Abstract of the Article :
The microbiome of the intestinal system is well-known as a modulatory factor. Having a balanced status of microbiota could help to prevent diseases, especially cancers related to the gastrointestinal system. We investigated the effects of <i>Lactobacillus rhamnosus</i> (<i>Lr</i>) and capecitabine o...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1080/01635581.2021.2014901
データ提供:米国国立医学図書館(NLM)
Lactobacillus rhamnosus R0011: A Potential Ally in Colon Cancer Treatment
The intricate balance of the gut microbiome plays a pivotal role in maintaining health and preventing disease. This study explores the potential of Lactobacillus rhamnosus (Lr) R0011, a probiotic strain, in enhancing the efficacy of capecitabine, a chemotherapy drug, against colon cancer. Researchers investigated the effects of Lr and capecitabine on tumor size and other physiological parameters in a murine model of colon cancer. The findings suggest that Lr supplementation may enhance the effectiveness of capecitabine in treating colon cancer, potentially improving treatment outcomes and mitigating side effects. It's like a desert oasis, providing nourishment and support to a weary traveler.
Lr R0011: A Promising Adjunct to Colon Cancer Treatment
The study suggests that Lr R0011 may enhance the efficacy of capecitabine in treating colon cancer, potentially improving treatment outcomes and mitigating side effects. This research holds promise for developing more effective and tolerable treatment strategies for colon cancer patients. It's a beacon of hope in the ongoing battle against this disease, like a star guiding travelers through the vastness of the desert.
The Power of Probiotics in Cancer Treatment
This study highlights the potential role of probiotics in enhancing cancer treatment outcomes. The findings encourage further research to explore the specific mechanisms by which probiotics can modulate the gut microbiome and influence cancer progression. It's a reminder that the gut microbiome plays a crucial role in health and disease, and understanding its intricate dynamics can lead to new therapeutic approaches.
Dr.Camel's Conclusion
The findings of this study suggest that Lactobacillus rhamnosus R0011 may be a valuable adjunct to capecitabine treatment for colon cancer. The probiotic's potential to enhance treatment efficacy and mitigate side effects warrants further investigation. This research highlights the crucial role of the gut microbiome in health and disease, opening new avenues for developing more effective and personalized treatment strategies for cancer patients.
Date :
- Date Completed 2022-07-04
- Date Revised 2022-12-07
Further Info :
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