[Orolingual Angioedema after Recombinant Tissue Plasminogen Activator Treatment in Acute Cardiogenic Cerebral Embolism Patient Using Olmesartan: A Case Report].

Author: ArakiRyosuke, HamamotoTomoyuki, MinamiChisa, YamadaHideki

Paper Details 
Original Abstract of the Article :
Recombinant tissue plasminogen activator (rt-PA), which is used to treat acute cerebral infarction, may cause angioedema immediately after administration particularly in patients who are taking angiotensin-converting enzyme (ACE) inhibitors. On the other hand, unlike ACE inhibitors, angiotensin II r...See full text at original site
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引用元:
https://doi.org/10.1248/yakushi.21-00136

データ提供:米国国立医学図書館(NLM)

Orolingual Angioedema: A Sandstorm in the Body

Recombinant tissue plasminogen activator (rt-PA) is a life-saving medication for patients experiencing acute cerebral infarction. However, it can sometimes trigger a rare side effect: orolingual angioedema, a swelling of the face, mouth, and throat. This study, like a detailed examination of a desert sandstorm, investigates a case of orolingual angioedema in a patient taking an angiotensin II receptor blocker (ARB) after rt-PA treatment.

A Curious Case

The researchers report the case of an 82-year-old male patient taking olmesartan, an ARB, who developed orolingual angioedema after receiving rt-PA. This finding, like uncovering a hidden sandstorm in the desert, suggests that ARBs, unlike ACE inhibitors, may not always be a safe alternative for patients at risk for bradykinin-related side effects. The study underscores the importance of being aware of potential drug interactions and carefully monitoring patients receiving rt-PA.

Navigating the Desert of Drug Interactions

This case report highlights the complexities of drug interactions, a hidden desert that can sometimes lead to unexpected and potentially dangerous consequences. It’s like navigating a desert landscape with hidden dangers, a constant reminder of the importance of careful monitoring and communication between patients and healthcare providers.

Dr.Camel's Conclusion

This study, like a warning sign in a dangerous desert, reminds us of the importance of being aware of potential drug interactions and their consequences. It's essential to carefully consider the risks and benefits of medications and to communicate any concerns with your healthcare provider. It’s about navigating the desert of drug interactions with caution and preparedness, ensuring a safe and successful journey.

Date :
  1. Date Completed 2022-01-31
  2. Date Revised 2022-01-31
Further Info :

Pubmed ID

34980751

DOI: Digital Object Identifier

10.1248/yakushi.21-00136

Related Literature

SNS
PICO Info
in preparation
Languages

Japanese

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