Treatment of periocular advanced basal cell carcinoma with Hedgehog pathway inhibitors: A single-center study and a new dedicated therapeutic protocol.

Author: De GiorgiVincenzo, DoniLaura, GuerriniLaura, MaioVincenza, MassiDaniela, MazziniCinzia, PierettiGiulia, SantoroNicola, ScarfìFederica, ScocciantiSilvia, SilvestriFlavia, SpinelliGiuseppe, TraneLuciana, VenturiFederico

Paper Details 
Original Abstract of the Article :
The management of difficult-to-treat periocular basal cell carcinoma (BCC) becomes very challenging in cases of delayed diagnosis, leading to the development of locally advanced BCC. The aim of this study was to evaluate the outcomes of Hedgehog pathway inhibitors (vismodegib and sonidegib) treatmen...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672118/

データ提供:米国国立医学図書館(NLM)

Tackling Periocular Advanced Basal Cell Carcinoma with Hedgehog Pathway Inhibitors

This research embarks on a journey through the challenging terrain of periocular advanced basal cell carcinoma (BCC), a complex condition akin to navigating a shifting sand dune. The study, an observational prospective single-center case series, explores the effectiveness of Hedgehog pathway inhibitors (HPIs) in treating this type of BCC. The researchers found that HPIs resulted in regression or stabilization of the neoplasm in all patients, offering a promising approach to managing this complex condition.

HPIs – A Potentially Effective Tool for Managing BCC

The study reveals a promising finding – HPIs demonstrate potential as an effective tool for managing periocular advanced BCC. These inhibitors, like navigating a desert with a guide, offer a potential path to improved outcomes for patients battling this challenging condition.

Navigating Periocular Advanced BCC

This research highlights the importance of seeking early medical attention if you suspect a BCC. Prompt diagnosis and treatment can greatly improve outcomes and prevent complications. Understanding the potential benefits of HPIs in managing BCC can empower individuals to make informed decisions about their healthcare.

Dr.Camel's Conclusion

This research offers valuable insights into the potential benefits of Hedgehog pathway inhibitors in treating periocular advanced BCC. The study highlights the need for ongoing investigation into this promising treatment approach. This research serves as a guidepost, pointing towards a future where HPIs may play a significant role in managing BCC and improving patient outcomes.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-01-11
Further Info :

Pubmed ID

35003569

DOI: Digital Object Identifier

PMC8672118

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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