Antiangiogenic Compound Axitinib Demonstrates Low Toxicity and Antitumoral Effects against Medulloblastoma.

Author: DaubonThomas, DerieppeMarie-Alix, DoyenJérôme, DurivaultJérôme, GavardJulie, GrépinRenaud, MartialSonia, MontemagnoChristopher, Pagnuzzi-BoncompagniMarina, PagèsGilles, PiccoVincent, Planas-BielsaVictor, VandenbergheAshaina, VialValérie

Paper Details 
Original Abstract of the Article :
Despite the improvement of medulloblastoma (MB) treatments, survivors face severe long-term adverse effects and associated morbidity following multimodal treatments. Moreover, relapses are fatal within a few months. Therefore, chemotherapies inducing fewer adverse effects and/or improving survival a...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750527/

データ提供:米国国立医学図書館(NLM)

Targeting Medulloblastoma: A New Approach to Combating a Deadly Brain Cancer

Medulloblastoma, a malignant brain tumor that predominantly affects children, poses a significant challenge for clinicians. While treatments have progressed, the long-term side effects and potential for relapse remain major concerns. This study explores the potential of antiangiogenic drugs, specifically axitinib, as a promising therapeutic strategy for treating medulloblastoma. The study focuses on the importance of developing treatment strategies that minimize adverse effects and improve survival rates, especially in the case of relapse.

Beyond the Conventional: Exploring New Avenues for Medulloblastoma Treatment

This study highlights the need for a multifaceted approach to combatting medulloblastoma. Researchers are exploring alternative treatment strategies, such as antiangiogenic therapies, to address the limitations of current treatments. The study suggests that axitinib, a last-generation antiangiogenic drug, holds promise as a potential treatment option for medulloblastoma. The researchers are investigating the efficacy and safety profile of axitinib in preclinical models, paving the way for future clinical trials to evaluate its effectiveness in human patients.

Hope on the Horizon: A New Era of Medulloblastoma Treatment

This research offers a glimmer of hope for patients with medulloblastoma. By investigating novel antiangiogenic drugs, researchers are pushing the boundaries of cancer treatment and seeking to improve outcomes for patients. This study serves as a reminder that continued research and innovation are vital to combatting this challenging disease.

Dr.Camel's Conclusion

This study, like a desert flower blooming amidst harsh conditions, represents a promising advancement in the fight against medulloblastoma. It underscores the importance of exploring novel therapeutic strategies and the potential of antiangiogenic drugs in improving outcomes for patients.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-01-14
Further Info :

Pubmed ID

35008234

DOI: Digital Object Identifier

PMC8750527

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English

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