Side effects that occurred early in people with multiple sclerosis during the first year of treatment with cladribine tablets: a plain language summary.

Author: AldridgeJulie, DangondFernando, GiovannoniGavin, JackDominic, LebsonLori A, LeistThomas P, NoltingAxel, OhJiwon, WalkerBryan

Paper Details 
Original Abstract of the Article :
People with multiple sclerosis (also shortened to MS) may have difficulties staying on treatment due to side effects. Cladribine tablets, approved for treating relapsing forms of MS, are given by mouth for four short periods over two years. The benefit of convenient dosing may be lost if side effect...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.2217/nmt-2021-0041

データ提供:米国国立医学図書館(NLM)

Cladribine Tablets for Multiple Sclerosis: Side Effects and Treatment Adherence

This study examines the side effects associated with cladribine tablets, a medication used to treat relapsing forms of multiple sclerosis (MS). The researchers aimed to determine the frequency and severity of side effects observed during the first year of treatment, specifically focusing on the initial 12 weeks of treatment. The study's findings provide important insights into the safety profile of cladribine tablets for MS patients, particularly regarding the early onset of side effects.

Cladribine Tablets: A Well-Tolerated Treatment Option

The study found that a significant proportion of participants who took cladribine tablets experienced drug-related side effects, but most were mild and did not lead to treatment discontinuation. While a smaller proportion of participants who took placebo experienced side effects, the majority of these were also mild. The study suggests that cladribine tablets are generally well-tolerated, with a low rate of treatment discontinuation due to side effects.

Navigating MS Treatment: Finding the Right Balance Between Benefits and Risks

This study highlights the importance of considering both the potential benefits and risks of cladribine tablets when making treatment decisions for MS patients. While the study found a relatively low rate of treatment discontinuation due to side effects, it is crucial for healthcare professionals to carefully monitor patients for potential adverse events and provide appropriate support to ensure treatment adherence and optimize patient outcomes.

Dr.Camel's Conclusion

This research is like a desert oasis offering a potential respite for those living with MS. While cladribine tablets may provide relief from the debilitating symptoms of MS, it's important to understand the potential side effects. This study provides valuable information for both patients and healthcare professionals to make informed decisions about treatment and navigate the complex journey of managing this challenging condition.

Date :
  1. Date Completed 2022-03-30
  2. Date Revised 2022-04-25
Further Info :

Pubmed ID

35019731

DOI: Digital Object Identifier

10.2217/nmt-2021-0041

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.