Paper Details 
Original Abstract of the Article :
Secondary antibiotic prophylaxis with regular intramuscular benzathine penicillin G (BPG) is the cornerstone of rheumatic heart disease management. However, there is a growing body of evidence that patients with rheumatic heart disease who have severe valvular heart disease with or without reduced v...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075066/

データ提供:米国国立医学図書館(NLM)

Penicillin Reactions in Patients with Rheumatic Heart Disease

This advisory from the American Heart Association addresses the growing concern about penicillin reactions in patients with rheumatic heart disease. The authors highlight the potential risks of intramuscular benzathine penicillin G (BPG) injections, specifically cardiovascular compromise, in patients with severe valvular heart disease. They provide recommendations for risk stratification and risk reduction strategies, including the consideration of oral prophylaxis for patients at elevated risk.

Balancing the Scales of Benefit and Risk

This advisory emphasizes the importance of carefully balancing the benefits and risks of penicillin prophylaxis for patients with rheumatic heart disease. The authors' recommendations aim to mitigate the potential risks of BPG injections, particularly in patients with severe valvular heart disease, while ensuring adequate protection against rheumatic fever.

Navigating the Shifting Sands of Treatment Decisions

The researchers likened the decision-making process for treating rheumatic heart disease to navigating a shifting desert landscape. Just as a traveler must carefully choose their path based on the changing terrain, clinicians must carefully consider the individual patient's needs and the potential risks and benefits of various treatment options. This advisory provides valuable guidance for making informed treatment decisions, emphasizing the need for a personalized approach.

Dr.Camel's Conclusion

This advisory from the American Heart Association sheds light on the critical issue of penicillin reactions in patients with rheumatic heart disease. By providing clear guidelines for risk stratification and risk reduction, the authors aim to ensure the safety and well-being of patients while maintaining effective prophylaxis against rheumatic fever. This advisory underscores the importance of individualized treatment approaches and the need for ongoing dialogue between clinicians and patients to ensure the best possible outcomes.

Date :
  1. Date Completed 2022-04-08
  2. Date Revised 2023-08-09
Further Info :

Pubmed ID

35049336

DOI: Digital Object Identifier

PMC9075066

Related Literature

SNS
PICO Info
in preparation
Languages

English

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