Reversible Toxic Encephalopathy Involving the Cerebellum and Subcortical White Matter Attributed to Capecitabine.

Author: LiYongchang, TangXiangqi, WuXiaomei, ZhongWei

Paper Details 
Original Abstract of the Article :
Capecitabine is an anticancer drug related to 5-fluorouracil (5-FU) that is used to treat multiple cancers. Little is known about the central nervous system toxicity of capecitabine owing to the low frequency of occurrence. In this report we describe a rare case of capecitabine-related toxic encepha...See full text at original site
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引用元:
https://doi.org/10.1016/j.amjms.2021.10.028

データ提供:米国国立医学図書館(NLM)

Capecitabine-Related Toxic Encephalopathy: A Case Report

This case report describes a rare instance of [toxic encephalopathy] attributed to [capecitabine], an anticancer drug. The authors present a detailed case study of a patient who developed reversible toxic encephalopathy involving the cerebellum and subcortical white matter after receiving capecitabine treatment. This report highlights the importance of recognizing and managing potential neurological complications associated with capecitabine therapy.

Navigating the Potential Risks of Capecitabine

This case report serves as a reminder that even seemingly well-tolerated medications like capecitabine can have rare but serious side effects. The authors emphasize the importance of early detection and prompt intervention when neurological complications arise. They suggest that prescreening for dihydropyrimidine dehydrogenase genotype variants and monitoring 5-FU degradation rates may help to minimize the risk of toxic reactions.

Understanding Capecitabine Therapy

Capecitabine is a valuable tool in the fight against cancer, but it's important to be aware of its potential risks. This case report underscores the importance of close monitoring and prompt management of any neurological complications. It's essential to have open communication with your healthcare provider about any concerns or symptoms you experience during capecitabine therapy. Just as a desert traveler must be vigilant about potential dangers, we must be mindful of the potential side effects of any medication.

Dr.Camel's Conclusion

This case report serves as a reminder of the importance of vigilance in cancer treatment. While capecitabine is a valuable therapeutic option, it's essential to be aware of its potential neurological side effects and to seek medical attention promptly if any concerns arise. Remember, knowledge is power, and understanding the potential risks associated with any treatment can empower us to make informed decisions about our health.

Date :
  1. Date Completed 2022-04-12
  2. Date Revised 2022-05-31
Further Info :

Pubmed ID

35114182

DOI: Digital Object Identifier

10.1016/j.amjms.2021.10.028

Related Literature

SNS
PICO Info
in preparation
Languages

English

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