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Effect of Mg-Gluconate on the Osmotic Fragility of Red Blood Cells, Lipid Peroxidation, and Ca<sup>2+</sup>-ATPase (PMCA) Activity of Placental Homogenates and Red Blood Cell Ghosts From Salt-Loaded Pregnant Rats.
Author: AbadCilia, ChiarelloDelia I, MarínReinaldo, MedinaYollyseth, PiñeroSandy, ProverbioFulgencio, RojasDeliana
Original Abstract of the Article :
Preeclampsia (PE) is a pregnancy-specific syndrome with multisystem involvement which leads to fetal, neonatal, and maternal morbidity and mortality. A model of salt-loaded pregnant rats has been previously studied, sharing several pathological characteristics of preeclamptic women. In this study, i...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829449/
データ提供：米国国立医学図書館（NLM）
Magnesium Gluconate: A Potential Treatment for Preeclampsia?
Preeclampsia, a serious pregnancy complication, can lead to significant health risks for both mother and baby. Magnesium sulfate (MgSO4) is currently the standard treatment for preeclampsia, but it has limitations. This study investigates the potential of magnesium gluconate (Mg-gluconate) as an alternative treatment for preeclampsia. Researchers compared the effects of Mg-gluconate to MgSO4 on red blood cell fragility, lipid peroxidation, and calcium-ATPase (PMCA) activity in a model of salt-loaded pregnant rats, which exhibit some features of preeclampsia.
Magnesium Gluconate: A Potential Alternative to Magnesium Sulfate
The study found that Mg-gluconate effectively reduced red blood cell fragility, lipid peroxidation, and decreased PMCA activity in salt-loaded pregnant rats, similar to the effects of MgSO4. These findings suggest that Mg-gluconate may be a viable alternative to MgSO4 for treating preeclampsia. This research is like finding a hidden well in a desert, a source of potential therapeutic benefit that could improve the management of preeclampsia.
Magnesium Gluconate: Exploring New Treatment Options for Preeclampsia
This study provides valuable insights into the potential benefits of Mg-gluconate for preeclampsia. It's like discovering a new path through a desert, a path that could lead to improved treatment options for this serious condition. Further research is needed to confirm the clinical efficacy of Mg-gluconate in pregnant women with preeclampsia.
Dr.Camel's Conclusion
This study offers a promising alternative to magnesium sulfate for managing preeclampsia. It's like finding a hidden oasis in a desert, providing a new source of potential therapeutic benefit. Further research is needed to confirm the efficacy and safety of Mg-gluconate in human patients, but it holds significant promise for improving the management of this complex pregnancy complication.
Date :
- Date Completed n.d.
- Date Revised 2022-02-16
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