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Comparison of the effect of prayer and ginger on the severity of pain and anxiety in inpatients with burn: Palliative care.

Author: BoroujeniLotfolah Afzali, Hasanpour DehkordiAli, NoormohammadiMohamad Reza

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study found that prayer and ginger were both effective in reducing pain and anxiety in burn patients. Pain levels were lower in the prayer and ginger groups at days 3 and 6 of hospitalization compared to the control group. The prayer group had significantly lower anxiety levels than the ginger group on day 6. These findings suggest that prayer and ginger are safe, cost-effective alternatives for managing pain and anxiety in burn patients.
Paper Details　
Original Abstract of the Article :
BACKGROUND AND AIM: One of the symptoms of burning is chronic and severe pain that affects the quality of life of patients. The aim of this article was to compare of the effect of prayer and ginger on the severity of pain and anxiety in inpatients with burn. METHODS: This study is a clinical trial ...See full text at original site
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引用元：
https://doi.org/10.32394/pe.75.40

データ提供：米国国立医学図書館（NLM）

TDP-43: A Shifting Dune in the Desert of Neurological Disorders

TDP-43, a protein involved in various cellular processes, has been implicated in the development of neurodegenerative diseases like amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). This study examines the impact of low-level overexpression of TDP-43 in a mouse model, mimicking the subtle increases observed in human patients. The researchers created transgenic mice that expressed TDP-43 at slightly elevated levels and monitored their development and behavior.

The Effects of TDP-43 Overexpression

The study found that low-level TDP-43 overexpression caused a reproducible progressive weakness ending in paralysis in mid-life. The mice also exhibited a range of neurological abnormalities, including neuron loss, demyelination, and neuroinflammation. These findings suggest that even modest increases in TDP-43 levels can trigger neurodegeneration and contribute to the development of ALS and other neurological disorders.

Understanding the Mechanisms of Neurological Disease

ALS and FTD are devastating diseases that currently have no cure. This study provides valuable insights into the role of TDP-43 in these conditions, offering potential targets for future therapies. By understanding the mechanisms of TDP-43-related neurodegeneration, we can develop more effective treatments for these debilitating diseases.

Dr.Camel's Conclusion

This study highlights the significant impact that even subtle changes in TDP-43 levels can have on the development of neurological disorders. The findings provide a critical step towards understanding the complex mechanisms of neurodegeneration and offer hope for the development of targeted therapies. Just as a small shift in the desert sands can create a ripple effect across the landscape, this research shows that subtle changes at the molecular level can have profound consequences for the human brain.
Date :
  1. Date Completed 2022-02-18
  2. Date Revised 2023-12-13
Further Info :

Pubmed ID

35170885

DOI: Digital Object Identifier

10.32394/pe.75.40

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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