Metronidazole Induced Cerebellar Toxicity: A Case Report.

Author: DhunganaKrishna, NiroulaAliska, PrajapatiRina, SapkotaShova, SharmaSubhani

Paper Details 
Original Abstract of the Article :
Metronidazole is a widely used antibiotic against bacterial and protozoan infections. Even though the therapeutic use of the drug is high, it is associated with some severe side effects like neurotoxicity such as optic neuropathy, peripheral neuropathy, encephalopathy and cerebellar toxicity. We pre...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107893/

データ提供:米国国立医学図書館(NLM)

Metronidazole: A Double-Edged Sword in the Fight Against Infections

The field of infectious disease research is constantly evolving. One important challenge in this field is finding safe and effective treatments that can combat various infections. This study delves into the potential side effects of metronidazole, a commonly used antibiotic. Using a case report approach, the authors investigate a particular case of cerebellar toxicity following metronidazole therapy. The researchers employed a combination of clinical observations, imaging techniques, and detailed patient history to understand the relationship between metronidazole and the observed neurological symptoms.

Metronidazole-Induced Cerebellar Toxicity: A Case Study Reveals a Possible Link

The study discovered that a 55-year-old male patient who had undergone metronidazole treatment for two months experienced dysarthria and cerebellar dysfunction. These symptoms resolved upon discontinuation of the drug. This finding suggests a potential link between metronidazole use and cerebellar toxicity. The case report provides valuable insights into the potential adverse effects of this commonly prescribed medication.

Think Before You Take: Implications for Patient Care

The results of this study highlight the importance of considering the potential side effects of medications, especially when treating patients with underlying health conditions. While metronidazole is effective in combating bacterial and protozoan infections, it's crucial to monitor patients closely for any neurological changes. This case highlights the need for careful monitoring and prompt discontinuation of the drug if such complications arise. The research suggests the importance of a careful assessment of patient risks and benefits when prescribing metronidazole.

Dr. Camel's Conclusion

Think of metronidazole as a camel crossing the desert. It can be a valuable companion, providing strength and support. However, like a camel in a harsh environment, metronidazole can also have unforeseen consequences. It's essential to be aware of these potential hazards and take appropriate precautions to ensure a smooth journey. The research underscores the need for caution when prescribing metronidazole, particularly when patients are already experiencing neurological conditions.

Date :
  1. Date Completed 2022-02-25
  2. Date Revised 2022-07-16
Further Info :

Pubmed ID

35199725

DOI: Digital Object Identifier

PMC9107893

Related Literature

SNS
PICO Info
in preparation
Languages

English

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