Paper Details

  1. Home
  2. Paper Details

[Acute myeloid leukemia (AML) in adults. Further development of therapy based on clinical phase II and phase III studies].

Author: BüchnerT, HiddemannW, KochP, KreutzmannH, KuseR, MaschmeyerG, MohrA, PielkenH J, UrbanitzD, WendtF

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This review of studies on acute myeloid leukemia (AML) in adults finds that while significant progress was made in treatment during the 1970s, there has been limited improvement in the 1980s. The authors advocate for a focus on analyzing different components and elements of AML treatment in order to improve their effectiveness. This includes standardizing treatment protocols and utilizing randomized controlled trials for comparisons. The authors highlight their own multi-center trial which contributed to understanding the role of maintenance chemotherapy and immunotherapy.
Paper Details　
Original Abstract of the Article :
By a review of relevant clinical studies on adult AML no substantial progress can be seen in the eighties so far. After the development of successful chemotherapy regimens during the seventies, further improvement can only be expected in small steps. Clinical studies, therefore, should concentrate o...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1159/000215970

データ提供：米国国立医学図書館（NLM）

Acute Myeloid Leukemia (AML) in Adults: A Search for Improved Treatment

This research examines the ongoing challenge of treating acute myeloid leukemia (AML), a type of cancer that affects the blood and bone marrow. It’s like a fierce desert wind, disrupting the normal balance of the body's cells. The study reviewed existing treatment strategies and highlighted the need for further research to improve outcomes. The researchers emphasized the importance of standardized treatments and the potential of immunotherapy in tackling this aggressive disease.

AML: A Need for Refined Treatment Strategies

This study reveals that, despite advancements in cancer treatment, AML remains a formidable challenge. It's like navigating a vast, unforgiving desert - the search for effective treatments continues. The study underscores the need for more research and development of new therapies, particularly those that target specific aspects of the disease.

AML: The Promise of Immunotherapy

This research highlights the potential of immunotherapy in the fight against AML. It's like a skilled oasis gardener, carefully cultivating the body's own defenses to combat the disease. This study encourages further exploration of immunotherapy as a promising avenue for improving outcomes for those with AML.

Dr.Camel's Conclusion

AML is a complex and challenging disease, but this research inspires hope for the future. Continued research and development, coupled with a focus on personalized treatment strategies, can bring us closer to finding effective and lasting solutions for those affected by AML. Just as camels adapt to survive in harsh desert environments, we can work together to overcome the challenges of this disease.

Date :
  1. Date Completed 1986-07-16
  2. Date Revised 2018-02-16
Further Info :

Pubmed ID

3520426

DOI: Digital Object Identifier

10.1159/000215970

SNS
PICO Info
in preparation
Languages

German

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.