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Effectiveness of rimantadine prophylaxis of children within families.

Author: AbellT D, CloverR D, CouchR B, CrawfordS A, GlezenW P, RamseyC N

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

Rimantadine prophylaxis effectively prevented influenza A infection in children. The infection rate was 2.9% in the rimantadine group compared to 31.7% in the placebo group. Rimantadine was well-tolerated with no significant difference in reported side effects between the two groups.
Paper Details　
Original Abstract of the Article :
With recent studies suggesting that children are the main introducers of influenza infections into families, we conducted a placebo-controlled, double-blind, randomized trial to study the prophylactic effectiveness of rimantadine hydrochloride in children on the transmission of influenza A infection...See full text at original site
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引用元：
https://doi.org/10.1001/archpedi.1986.02140210104036

データ提供：米国国立医学図書館（NLM）

Rimantadine: A Shield Against Influenza

This study investigates the [effectiveness of rimantadine] as a [prophylactic treatment] for [influenza A infections] in [children]. The researchers conducted a [placebo-controlled, double-blind, randomized trial] to assess the impact of [rimantadine] on [transmission of influenza A within families]. The results demonstrate the [effectiveness of rimantadine prophylaxis] in [preventing influenza A infection] in [children].

Protecting Children from Influenza

This research reveals that [rimantadine prophylaxis] is a [valuable tool] for [preventing influenza A infection in children]. The study found that [significantly fewer children] in the [rimantadine group] developed [influenza A infection] compared to the [placebo group].

Rimantadine and Influenza: A Family Affair

This study highlights the importance of [prophylactic measures] in [preventing the spread of influenza] within [families]. The study suggests that [rimantadine prophylaxis in children] could be a [effective strategy] for [reducing influenza A transmission] in [families].

Dr.Camel's Conclusion

Think of rimantadine as a sturdy camel caravan, protecting children from the harsh desert winds of [influenza A]. This study sheds light on the importance of [prophylactic measures] in [keeping families healthy] during [influenza season]. Always consult with your doctor before using any medication, especially for children.

Date :
  1. Date Completed 1986-07-21
  2. Date Revised 2019-07-16
Further Info :

Pubmed ID

3521258

DOI: Digital Object Identifier

10.1001/archpedi.1986.02140210104036

Related Literature

Article Analysis
・Side Effects of rimantadine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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