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Antipsychotic Use During Pregnancy and Risk for Gestational Diabetes: A National Register-Based Cohort Study in Sweden.

Author: ForsbergLisa, HeinonenEssi, KällénKarin, NörbyUlrika, WideKatarina

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This Swedish national register-based cohort study investigated the association between antipsychotic use during pregnancy and gestational diabetes. Olanzapine, clozapine, and quetiapine were associated with increased risks for gestational diabetes and the infant being large for gestational age. Enhanced metabolic monitoring should be considered for pregnant women using these drugs.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: We aimed to study whether antipsychotic use during pregnancy is associated with gestational diabetes. METHODS: This was a Swedish national register-based cohort study on the Medical Birth Register and the Prescribed Drug Register including all 1,307,487 singleton births between July 2006...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095513/

データ提供：米国国立医学図書館（NLM）

Antipsychotics and Gestational Diabetes: A Cause for Concern?

The field of [maternal health] is constantly seeking to understand the impact of [various factors] on pregnancy outcomes. This study examines the [association between antipsychotic use during pregnancy and the risk of gestational diabetes]. Researchers analyzed data from a [Swedish national register-based cohort study], finding [a significant association between high-risk metabolic second-generation antipsychotics (olanzapine, clozapine, and quetiapine) and an increased risk of gestational diabetes]. While other antipsychotics did not show a similar association, this research raises concerns about [the potential metabolic effects of certain antipsychotics during pregnancy].

A Deeper Dive into Antipsychotic Use During Pregnancy

The findings of this study suggest that [women using specific antipsychotics during pregnancy should be monitored closely] for [metabolic complications]. The researchers found [a 2.2-fold increase in the risk of gestational diabetes] for women using high-risk metabolic second-generation antipsychotics, highlighting the importance of [early identification and intervention] to manage these potential risks.

Understanding the Impact of Antipsychotics on Pregnancy

If you are [pregnant or planning a pregnancy] and are taking [antipsychotic medication], it's crucial to [discuss your treatment plan] with your doctor. This research provides valuable information about [the potential risks and benefits] of different antipsychotics during pregnancy, allowing you to [make informed decisions] about your health and the well-being of your child.

Dr. Camel's Conclusion

Just like a desert oasis provides a crucial source of water for weary travelers, understanding the potential impact of medications during pregnancy is essential for navigating the journey to motherhood. This study serves as a reminder to stay hydrated with knowledge and collaborate with your healthcare team to make informed decisions about your care.

Date :
  1. Date Completed 2022-05-17
  2. Date Revised 2022-11-30
Further Info :

Pubmed ID

35220525

DOI: Digital Object Identifier

PMC9095513

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Article Analysis
・Side Effects of quetiapine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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