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Original Abstract of the Article :
Twelve patients with bronchial asthma participated in a blind, randomized, crossover study comparing the effects of 500 micrograms terbutaline in one inhalation, 125 micrograms in four inhalations taken in rapid succession, and 125 micrograms in four inhalations taken with an intervening time interv...See full text at original site
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引用元:
https://doi.org/10.1159/000194906
データ提供:米国国立医学図書館(NLM)
Optimizing Bronchodilator Delivery: A Quest for Efficiency
Bronchodilators are essential medications for managing asthma, but their effectiveness can vary depending on the delivery method and dosage. This study explores the impact of dividing a single dose of terbutaline, a common bronchodilator, into multiple inhalations with different time intervals between each inhalation, on lung function. The researchers investigated whether dividing the dose into smaller, more frequent inhalations could enhance the medication's effectiveness.
Time is of the Essence: A Closer Look at Dosage Regimens
The study found that the timing of inhaled doses significantly influenced the medication's effectiveness. While dividing the dose into multiple inhalations did not result in a significantly greater bronchodilation effect compared to a single inhalation, it did highlight the importance of timing. The researchers concluded that the chosen time interval between divided doses might have been too long to achieve maximum accumulated effect. These findings suggest that further research is needed to determine optimal dosage regimens for inhaled bronchodilators, considering both the number of inhalations and the time intervals between them.
Fine-Tuning Treatment: A Personalized Approach to Asthma Management
This study underscores the importance of optimizing treatment for asthma by considering the individual patient's needs and response to medication. It highlights the need for a careful evaluation of different dosage regimens and delivery methods to ensure optimal effectiveness and minimize side effects. These findings provide valuable insights for healthcare providers seeking to personalize asthma management plans.
Dr. Camel's Conclusion
Like a desert wind shifting the dunes, the effectiveness of asthma medications can be influenced by subtle changes in delivery and timing. This study emphasizes the importance of finding the right balance for each individual, ensuring that medication delivery is not only effective but also efficient. Just as we adapt our travels to the changing desert landscape, we must tailor our asthma treatment plans to the unique needs of each patient.
Date :
- Date Completed 1986-07-25
- Date Revised 2018-02-16
Further Info :
English
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