Elexacaftor, tezacaftor and ivacaftor: a case of severe rash and approach to desensitisation.

Author: BakerOlivia, ChengAnn, HillUta

Paper Details 
Original Abstract of the Article :
We present a case of severe rash following induction of elexacaftor, tezacaftor and ivacaftor (ELX/TEZ/IVA) in a young adult male cystic fibrosis patient. While rash is a commonly reported side effect which resolves in 1-2 weeks with minimal intervention, our patient had presented with fever and wid...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895886/

データ提供:米国国立医学図書館(NLM)

Managing Severe Rash with Elexacaftor, Tezacaftor, and Ivacaftor Triple Therapy

Elexacaftor, tezacaftor, and ivacaftor (ELX/TEZ/IVA) triple therapy is a transformative treatment for cystic fibrosis patients. However, it is not without side effects, and rash is a commonly reported adverse event. This case report describes a young adult male cystic fibrosis patient who experienced a severe rash following the initiation of ELX/TEZ/IVA therapy. The patient's case highlights the potential for severe reactions and the need for careful monitoring. The researchers were able to successfully desensitize the patient to ELX/TEZ/IVA, allowing him to experience the benefits of this life-changing therapy. This case illustrates the importance of personalized medicine and the need for tailored approaches to managing drug-related adverse events.

Desensitization Strategies: A Solution for Drug-Related Adverse Events

This case report highlights the importance of desensitization strategies in managing drug-related adverse events. The researchers successfully desensitized the cystic fibrosis patient to ELX/TEZ/IVA triple therapy after experiencing a severe rash, allowing him to access the benefits of this life-changing treatment. This approach showcases the value of individualized care and the need for tailored approaches to managing drug-related side effects.

Personalized Medicine: A Key to Optimizing Treatment Outcomes

This case study is a compelling example of the importance of personalized medicine in managing drug-related adverse events. The patient's experience underscores the need for tailored approaches and desensitization strategies to optimize treatment outcomes and ensure the safety and well-being of patients. This case is a powerful reminder that a one-size-fits-all approach to treatment is often not sufficient.

Dr.Camel's Conclusion

Navigating the complex world of medication, especially for chronic conditions like cystic fibrosis, requires careful consideration and personalized care. This case study exemplifies the challenges and triumphs of managing drug-related adverse events. The researchers' success in desensitizing the patient to ELX/TEZ/IVA therapy highlights the importance of tailored approaches and the promise of personalized medicine for optimizing treatment outcomes and improving the lives of patients.
Date :
  1. Date Completed 2022-03-04
  2. Date Revised 2022-03-23
Further Info :

Pubmed ID

35236685

DOI: Digital Object Identifier

PMC8895886

SNS
PICO Info
in preparation
Languages

English

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