Effects of chronic mirabegron treatment on metabolic and cardiovascular parameters as well as on atherosclerotic lesions of WHHL rabbits with high-fructose high-fat diet-induced insulin resistance.

Author: BouhsinaNora, DagherElie, DesfontisJean-Claude, LalanneValérie, MallemM Yassine, MoughaizelMichelle, ThorinChantal

Paper Details 
Original Abstract of the Article :
Label="BACKGROUND AND AIM" NlmCategory="OBJECTIVE">Metabolic syndrome (MetS) is a global health and economic burden. Finding a suitable pharmacological approach for managing this syndrome is crucial. We explored the therapeutic potential of mirabegron (MIR), a &#946;<sub>3</sub>-adrenergic receptor ...See full text at original site
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引用元:
https://doi.org/10.1016/j.ejphar.2022.174870

データ提供:米国国立医学図書館(NLM)

Mirabegron: A Potential Oasis in the Desert of Metabolic Syndrome and Cardiovascular Disease

This research explores the complex and often interconnected landscape of metabolic syndrome (MetS), a global health concern that increases the risk of cardiovascular disease (CVD). The study investigates the potential of mirabegron, a β3-adrenergic receptor agonist, as a repurposed agent for managing MetS and its cardiovascular consequences, exploring its potential to offer a beacon of hope in this challenging environment.

The Desert of Metabolic Syndrome: Mirabegron Shows Promise

This research suggests that mirabegron, a β3-adrenergic receptor agonist, may hold promise as a repurposed agent for managing MetS and its associated cardiovascular risks. The study's findings indicate that mirabegron can favorably impact metabolic and cardiovascular parameters, potentially offering a valuable tool for mitigating the complications of MetS.

Navigating the Desert: Mirabegron as a Potential Therapeutic Strategy

The study underscores the potential of mirabegron as a promising therapeutic strategy for managing MetS and its cardiovascular complications. It highlights the need for further research to fully understand the mechanisms of action and long-term effects of mirabegron in this context. The study's findings encourage further exploration of mirabegron as a potential treatment option for individuals with MetS, aiming to create a more fertile and healthier landscape for those facing these challenges.

Dr. Camel's Conclusion

This research provides a glimmer of hope in the vast and often treacherous desert of metabolic syndrome and cardiovascular disease. The study's findings suggest that mirabegron, a β3-adrenergic receptor agonist, may offer a potential oasis of relief for individuals struggling with these conditions. The study encourages further exploration of mirabegron as a repurposed agent for managing MetS and its cardiovascular complications, aiming to create a more fertile and healthier environment for those facing these challenges.

Date :
  1. Date Completed 2022-04-07
  2. Date Revised 2022-04-07
Further Info :

Pubmed ID

35257716

DOI: Digital Object Identifier

10.1016/j.ejphar.2022.174870

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Article Analysis
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PICO Info
in preparation
Languages

English

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