An Evaluation of the Efficacy and Safety of Vibegron in the Treatment of Overactive Bladder.

Author: FrankelJeffrey, Haag-MolkentellerCornelia, JankowichRachael A, KennellyMichael J, StaskinDavid, VaranoSusann

Paper Details 
Original Abstract of the Article :
Pharmacologic treatment for overactive bladder (OAB), which is characterized by bothersome symptoms such as urgency and urge urinary incontinence (UUI), includes anticholinergics and &#946;<sub>3</sub>-adrenergic receptor agonists. Anticholinergics are associated with adverse effects including dry m...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901416/

データ提供:米国国立医学図書館(NLM)

Vibegron for Overactive Bladder: A Promising New Treatment Option

Overactive bladder (OAB) is a common condition affecting millions worldwide. Traditional treatments, such as anticholinergics, often come with undesirable side effects. This research delves into the efficacy and safety of vibegron, a new β3-adrenergic receptor agonist, as a potential alternative for OAB management. The study analyzes data from two phase 3 clinical trials (EMPOWUR and EMPOWUR extension) that examined the effects of vibegron on OAB symptoms.

Vibegron Demonstrates Positive Outcomes for Overactive Bladder

The results of the EMPOWUR trials show that vibegron is effective in improving OAB symptoms, including urgency, frequency, and urge urinary incontinence. This effect was observed as early as two weeks into the study and was sustained for the duration of the trials. Additionally, vibegron was generally safe and well-tolerated, showing no significant impact on blood pressure or heart rate.

A New Oasis in the Desert of Bladder Problems

This research offers a ray of hope for those struggling with OAB. Vibegron presents a potential treatment option with minimal side effects, providing a much-needed respite from the dry and uncomfortable symptoms of OAB. It's like finding a fresh spring in the desert – a source of relief and comfort.

Dr.Camel's Conclusion

This study highlights the ongoing search for new and improved treatments for common conditions like OAB. It's important to remember that while new medications offer promise, they should be used under the guidance of a healthcare professional. Just as a camel must choose its path carefully in the desert, we must be mindful of our health choices and seek expert advice.
Date :
  1. Date Completed n.d.
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

35264853

DOI: Digital Object Identifier

PMC8901416

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Languages

English

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