An Update on African Trypanocide Pharmaceutics and Resistance.

Author: KasoziKeneth Iceland, MacLeodEwan Thomas, NtulumeIbrahim, WelburnSusan Christina

Paper Details 
Original Abstract of the Article :
African trypanosomiasis is associated with <i>Trypanosoma evansi, T. vivax, T. congolense</i>, and <i>T. brucei</i> pathogens in African animal trypanosomiasis (AAT) while <i>T. b gambiense</i> and <i>T. b rhodesiense</i> are responsible for chronic and acute human African trypanosomiasis (HAT), res...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959112/

データ提供:米国国立医学図書館(NLM)

The Challenges of Trypanosomiasis Treatment

Trypanosomiasis, a parasitic disease endemic to Africa, presents a formidable challenge, like navigating a scorching desert where the sand is constantly shifting. This review, like a seasoned traveler with a deep understanding of this terrain, examines the current state of trypanocide pharmaceutics and the growing threat of drug resistance. The authors discuss the mechanisms of action of various trypanocides, their limitations, and the urgent need for novel therapies to combat this devastating disease.

The Evolving Landscape of Trypanosomiasis Treatment

This review, like a camel caravan adapting to changing desert conditions, highlights the dynamic nature of trypanocide resistance. The emergence of drug-resistant strains underscores the need for continued research and development of new therapies to address this evolving challenge.

Combating Trypanosomiasis in the 21st Century

The fight against trypanosomiasis, like a desert oasis striving for survival, requires persistent effort and innovative solutions. This review emphasizes the urgent need for collaborative research and development to address the challenges posed by drug resistance, ensuring that effective treatments remain available to those in need.

Dr.Camel's Conclusion

Trypanosomiasis, a parasitic disease that affects millions in Africa, presents a formidable challenge, much like a scorching desert where the sand is constantly shifting. This review, like a camel caravan traversing this challenging landscape, highlights the complexities of trypanocide pharmaceutics and the urgent need for novel therapies. The emergence of drug resistance, like a mirage that constantly shifts and disappears, underscores the importance of sustained research and development efforts to combat this devastating disease.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-04-01
Further Info :

Pubmed ID

35356785

DOI: Digital Object Identifier

PMC8959112

Related Literature

SNS
PICO Info
in preparation
Languages

English

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