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A Maximum-Use Trial of Ruxolitinib Cream in Adolescents and Adults with Atopic Dermatitis.
Author: BissonnetteRobert, CallRobert S, GongXiaohua, LeeMark, RaoofTooraj, YeleswaramSwamy, ZhuZhaoyin
Original Abstract of the Article :
BACKGROUND: Ruxolitinib cream is a topical formulation of ruxolitinib, an inhibitor of Janus kinase 1 and Janus kinase 2. OBJECTIVE: We aimed to determine the safety, tolerability, and bioavailability of 1.5% ruxolitinib cream under maximum-use conditions in patients with atopic dermatitis. Efficac...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142470/
データ提供:米国国立医学図書館(NLM)
A New Cream for Atopic Dermatitis: Ruxolitinib Cream
This study delves into the world of atopic dermatitis, a skin condition that causes itchy, red, and inflamed patches. Like a camel traversing the vast desert searching for an oasis, researchers are constantly seeking effective treatments for this troublesome condition. This research, conducted in the USA and Canada, investigated the safety and effectiveness of a new cream containing ruxolitinib, a substance that blocks certain inflammatory pathways in the body. They tested this cream on a group of people with atopic dermatitis, applying it twice a day for 56 days.
Ruxolitinib Cream: A Promise for Relief
The study revealed that ruxolitinib cream was generally well-tolerated, with about one-third of the participants experiencing some side effects. The most significant finding is that the cream demonstrated a high level of effectiveness in reducing symptoms of atopic dermatitis, with a significant improvement observed in the majority of participants.
Good News for Those with Atopic Dermatitis
This research offers hope for individuals struggling with atopic dermatitis. The results suggest that ruxolitinib cream may be a safe and effective treatment option. It's important to remember that everyone responds differently to medications, so it's essential to consult with a dermatologist to determine if this cream is right for you.
Dr. Camel's Conclusion
This study is a step forward in the journey to find effective treatments for atopic dermatitis. The results suggest that ruxolitinib cream holds promise as a safe and effective treatment option. However, further research is needed to fully understand the long-term effects of this cream and to determine its optimal use in diverse patient populations.
Date :
- Date Completed 2022-05-31
- Date Revised 2022-08-04
Further Info :
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