Risk of Ocular Adverse Events Associated With Use of Phosphodiesterase 5 Inhibitors in Men in the US.

Author: EtminanMahyar, MaberleyDavid, MikelbergFrederick S, SodhiMohit

Paper Details 
Original Abstract of the Article :
A number of case reports and small epidemiologic studies have quantified the risk of ocular adverse events associated with the use of phosphodiesterase type 5 inhibitors (PDE5Is). However, results have been conflicting, and epidemiologic data on the risk of serous retinal detachment (SRD) and retina...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8990352/

データ提供:米国国立医学図書館(NLM)

Investigating the Ocular Side Effects of Phosphodiesterase 5 Inhibitors

The world of pharmaceuticals is a delicate dance, with potential benefits often accompanied by potential side effects. This study focuses on phosphodiesterase type 5 inhibitors (PDE5Is), commonly used for erectile dysfunction. Researchers are exploring the potential connection between PDE5Is and ocular adverse events, specifically serous retinal detachment (SRD) and retinal vascular occlusion (RVO). The authors analyzed existing case reports and small epidemiologic studies, highlighting the conflicting findings regarding the risk of these ocular complications. This research emphasizes the need for robust epidemiologic data to clarify the potential association between PDE5Is and ocular adverse events.

A Closer Look at Potential Ocular Risks

The study reveals a complex picture regarding the ocular risks associated with PDE5Is. While some studies suggest a potential link, others do not. This ambiguity underscores the need for further research to definitively assess the risk of SRD and RVO in men using PDE5Is.

Staying Vigilant for Ocular Health

This research underscores the importance of being aware of potential side effects associated with medications. While PDE5Is are often effective, it's essential for men to be aware of the potential ocular risks and communicate any changes in vision to their healthcare provider.

Dr. Camel's Conclusion

Navigating the vast desert of pharmaceutical knowledge can be like traversing a shifting sand dune. What appears clear one moment can become obscured by new findings the next. This study underscores the importance of continuous research and vigilance, ensuring that we understand both the benefits and potential risks of medications. Just as a wise traveler in the desert constantly assesses their surroundings, we must remain alert to the potential effects of our medications.

Date :
  1. Date Completed 2022-05-23
  2. Date Revised 2023-04-08
Further Info :

Pubmed ID

35389459

DOI: Digital Object Identifier

PMC8990352

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Languages

English

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