Case Report: Tyrosine Kinase Inhibitors Induced Lymphadenopathy in Desmoid Tumor Patients.

Author: CherixStephane, DigkliaAntonia, DolcanAna, KoulourisPantelis, MatterMaurice, OmoumiPatrick, PapadopoulosSotirios, Royer-ChardonClaire, TsoumakidouGeorgia

Paper Details 
Original Abstract of the Article :
Tyrosine kinase inhibitors (TKIs) are nowadays a valuable treatment of desmoid tumors, a rare mesenchymal neoplasm. Although many side effects of imatinib and pazopanib, commonly or rarely occurring, have been described, reactional lymphadenopathy has not yet been reported. In this publication, we r...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8984282/

データ提供:米国国立医学図書館(NLM)

A New Side Effect of Tyrosine Kinase Inhibitors: Lymphadenopathy in Desmoid Tumor Patients

This study explores a new potential side effect of tyrosine kinase inhibitors (TKIs), a class of drugs commonly used in treating desmoid tumors, a rare type of cancer. It reports two cases of patients treated with TKIs who developed lymphadenopathy, an enlargement of lymph nodes. This discovery raises important questions about the long-term safety of these medications and highlights the need for continued monitoring of patients receiving TKI treatment.

Lymphadenopathy: A New Challenge in Desmoid Tumor Treatment

The study's findings demonstrate the importance of careful monitoring for potential side effects during TKI treatment. The development of lymphadenopathy, while a new observation, can lead to further diagnostic investigations and potentially alter treatment strategies. This research provides valuable insights for clinicians treating desmoid tumor patients and emphasizes the need for ongoing vigilance in identifying and managing potential side effects.

Balancing Benefits and Risks: A Crucial Aspect of Cancer Treatment

This study reminds us that even with promising advancements in cancer treatment, it's crucial to be aware of the potential downsides. The discovery of this new side effect underscores the importance of balancing the benefits of TKI therapy with the risks of potential complications. This research emphasizes the need for ongoing research into the long-term safety and efficacy of TKI treatment for desmoid tumors.

Dr. Camel's Conclusion

As a researcher with a keen interest in the complexities of cancer treatment, I find this study to be a valuable contribution to our understanding of TKI therapy. It highlights the importance of careful monitoring for potential side effects and emphasizes the need for continued research to ensure the long-term safety and efficacy of these medications.

Date :
  1. Date Completed 2022-04-12
  2. Date Revised 2022-05-19
Further Info :

Pubmed ID

35399933

DOI: Digital Object Identifier

PMC8984282

Related Literature

SNS
PICO Info
in preparation
Languages

English

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