Paper Details

  1. Home
  2. Paper Details

Efficacies of FAEV and EMA/CO regimens as primary treatment for gestational trophoblastic neoplasia.

Author: FengFengzhi, JiMingliang, JiangShiyang, RenTong, WanXirun, XiangYang, YangJunjun, ZhaoJun

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This randomized controlled trial compared the efficacies and toxicities of the FAEV regimen (floxuridine, actinomycin D, etoposide, and vincristine) with the EMA/CO regimen (etoposide, methotrexate, actinomycin D, cyclophosphamide, and vincristine) for treating high-risk gestational trophoblastic neoplasia (GTN) in China.
Paper Details　
Original Abstract of the Article :
Guidelines recommend etoposide, methotrexate, actinomycin D (EMA)/cyclophosphamide, vincristine (CO) as first-line treatment for high-risk gestational trophoblastic neoplasia (GTN). However, the floxuridine, actinomycin D, etoposide and vincristine (FAEV) regimen is commonly used to treat these pati...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345879/

データ提供：米国国立医学図書館（NLM）

Gestational Trophoblastic Neoplasia: Comparing Treatment Regimens in the Desert of Cancer Therapy

Gestational trophoblastic neoplasia (GTN) is a rare but potentially life-threatening condition. This research compares the efficacy and toxicity of two chemotherapy regimens, FAEV and EMA/CO, as primary treatment for high-risk GTN. The authors conducted a randomized controlled trial to assess the effectiveness of each regimen. Their findings suggest that both regimens demonstrate similar efficacy in treating GTN, but FAEV may have a slightly higher risk of side effects.

Gestational Trophoblastic Neoplasia: Comparing Treatment Regimens in the Desert of Cancer Therapy

This study suggests that both FAEV and EMA/CO are effective treatment options for high-risk GTN. The study's findings highlight the importance of considering the potential side effects associated with each regimen and making individualized treatment decisions based on patient characteristics and risk factors.

Gestational Trophoblastic Neoplasia: Comparing Treatment Regimens in the Desert of Cancer Therapy

This research sheds light on the ongoing quest for effective and safe treatment options for GTN. The study provides valuable data for informing treatment decisions for patients with this challenging condition. It underscores the importance of balancing efficacy and toxicity in cancer therapy, ensuring that the benefits outweigh the risks.

Dr.Camel's Conclusion

This research provides valuable insights into the efficacy and toxicity profiles of FAEV and EMA/CO as primary treatment options for high-risk GTN. The study's findings highlight the importance of considering individual patient characteristics and risk factors when selecting the most appropriate treatment regimen. It underscores the ongoing need for research and development in this area, seeking to optimize treatment strategies for this rare but potentially life-threatening condition.

Date :
  1. Date Completed 2022-08-04
  2. Date Revised 2023-04-23
Further Info :

Pubmed ID

35459802

DOI: Digital Object Identifier

PMC9345879

Related Literature

Article Analysis
・Effects of floxuridine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.