Paper Details 
Original Abstract of the Article :
Despite a favorable effect of imatinib on glucose metabolism in animal models, human reports are inconsistent. We retrospectively studied the long-term effect of imatinib on fasting plasma glucose (FPG), glycated hemoglobin (HbA1C), LDL-cholesterol (LDL), and triglycerides (TGs) in a large HMO cohor...See full text at original site
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引用元:
https://doi.org/10.1080/10428194.2022.2068003

データ提供:米国国立医学図書館(NLM)

Imatinib: A Double-Edged Sword? Exploring Its Metabolic Effects

The field of [cancer treatment] is constantly seeking therapies that are both effective and well-tolerated by patients. This study examines the long-term effects of [imatinib], a targeted therapy used to treat certain types of cancer, on [glucose metabolism] and [lipid profiles] in a large cohort of patients.

Imatinib's Metabolic Effects: A Double-Edged Sword

The authors, like explorers venturing into a complex desert landscape, found that imatinib, like a double-edged sword, had both beneficial and potentially detrimental effects on metabolism. While imatinib significantly reduced [HbA1c], [FPG], [LDL], and [TG] levels in the study cohort, these effects, like a desert mirage, require careful consideration in the context of individual patients.

Imatinib's Impact: A Cautionary Tale for Clinicians

This study, like a desert traveler navigating shifting sands, highlights the need for careful monitoring of metabolic parameters in patients receiving imatinib. While imatinib offers potential metabolic benefits, its impact on individual patients, like a desert oasis that may or may not be truly life-sustaining, must be carefully assessed.

Dr. Camel's Conclusion

This study, like a camel caravan traversing a vast and unforgiving desert, reveals the complex interplay between imatinib and metabolic parameters. Imatinib, like a desert mirage that appears both promising and deceptive, requires careful consideration in the context of individual patients. This research, like a compass guiding explorers through a challenging landscape, emphasizes the importance of vigilant monitoring and individualized care in managing the metabolic impact of imatinib therapy.

Date :
  1. Date Completed 2022-10-10
  2. Date Revised 2022-12-22
Further Info :

Pubmed ID

35475716

DOI: Digital Object Identifier

10.1080/10428194.2022.2068003

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Languages

English

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