Paper Details

  1. Home
  2. Paper Details

Oseltamivir and acute hepatitis, reality association or coincidence?

Author: ChidichimoLuciana, GrecoFrancesca, GrecoSonia, MastroianniAntonio, MauroMaria Vittoria, UrsoFilippo, VangeliValeria

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Oseltamivir is an antiviral medication that inhibits influenza neuraminidase enzymes, active against both influenza A and B viruses. This is the first reported case in Italy linking the development of acute hepatitis and oseltamivir therapy, in a patient suffering from influenza H1N1 infection. This case report suggests that experts should consider adding potential serious liver reactions to the oseltamivir product label.
Paper Details　
Original Abstract of the Article :
Oseltamivir is an orally administered antiviral medication that selectively inhibits the influenza neuraminidase enzymes that are essential for viral replication and it is active against both influenza A and B viruses. Oseltamivir is indicated for therapy or post-exposure prevention of influenza A a...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1177/13596535211041494

データ提供：米国国立医学図書館（NLM）

Oseltamivir and Acute Hepatitis: A Case Report

This case report raises concerns about a potential link between oseltamivir, an antiviral medication used to treat influenza, and acute hepatitis. The study presents a case of a patient who developed acute hepatitis while taking oseltamivir, prompting further investigation into the drug's potential liver toxicity.

Oseltamivir: A Potential Liver Risk?

This study, like a camel encountering a hidden danger in the desert, explores a potential safety concern associated with oseltamivir. While oseltamivir is generally considered safe, this case report suggests that it may, in rare instances, contribute to liver injury. Further research is needed to confirm this association and to identify risk factors that might predispose individuals to liver complications.

Navigating Drug Safety: A Collaborative Approach

This case report highlights the importance of vigilant monitoring and reporting of potential drug-related adverse effects. It emphasizes the role of healthcare professionals and patients in working together to ensure drug safety. Physicians should be aware of potential liver toxicity associated with oseltamivir and should carefully monitor patients for any signs of liver problems during treatment.

Dr. Camel's Conclusion

This case report serves as a cautionary tale, reminding us that even well-established medications can have unexpected side effects. By staying informed and vigilant, we can work together to improve drug safety and ensure the well-being of patients.

Date :
  1. Date Completed 2022-05-02
  2. Date Revised 2022-06-07
Further Info :

Pubmed ID

35485329

DOI: Digital Object Identifier

10.1177/13596535211041494

Related Literature

Article Analysis
・Side Effects of oseltamivir
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.