Paper Details 
Original Abstract of the Article :
The present study aimed to assess the effect of Apremilast on experimentally induced hypertrophic scars in rabbits. A total of 40 healthy male New Zealand White rabbits between 6 and 12 months of age were assigned to four groups (n=10). Group I consists of apparently healthy control rabbit...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083860/

データ提供:米国国立医学図書館(NLM)

Apremilast: A Potential Remedy for the Scars of Time

Hypertrophic scars, those raised, unsightly reminders of past injuries, are a common concern. This research, like a desert explorer mapping new terrain, investigates the potential of Apremilast, a drug already used for psoriasis, as a treatment for these stubborn scars.

The study, conducted on rabbits, employs an experimental model of hypertrophic scars, creating a controlled environment to observe the effects of Apremilast. The researchers meticulously examine the scars' morphology, assessing inflammation, fibroblast activity, and collagen levels. They find that Apremilast, like a skilled desert sculptor, helps to sculpt the scars, reducing inflammation and fibroblast count, effectively diminishing the scar's prominence.

Apremilast's Promising Potential

The research demonstrates that Apremilast, like a skilled desert sculptor, can help to sculpt the scars, reducing inflammation and fibroblast count, effectively diminishing the scar's prominence. The results, like a desert oasis, offer hope for patients seeking a more aesthetically pleasing outcome after injury or surgery.

A Note of Caution and Hope

While the study paints a promising picture for Apremilast's potential, more research is needed to assess its effectiveness in humans and to optimize its dosage. However, the research offers hope for a future where the scars of time can be minimized, leaving behind a smoother, more confident landscape.

Dr.Camel's Conclusion

This study suggests that Apremilast may hold promise as a novel therapeutic agent for hypertrophic scars. Its ability to effectively reduce inflammation and fibroblast activity is encouraging, hinting at a future where the scars of our past may be less prominent, leaving us with a smoother and more confident exterior.

Date :
  1. Date Completed 2023-06-13
  2. Date Revised 2023-06-13
Further Info :

Pubmed ID

35546978

DOI: Digital Object Identifier

PMC9083860

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Languages

English

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