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Long-Term Outcomes among Adolescent and Young Adult Survivors of Acute Leukemia: A Surveillance, Epidemiology, and End Results Analysis.

Author: AndersenClark R, BerkmanAmy M, CuglievanBranko, DiNardoCourtney D, JainNitin, KadiaTapan M, LivingstonJ A, LupoPhilip J, McCallDavid C, ParsonsSusan K, RothMichael E, ShortNicholas J

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study assessed long-term mortality outcomes of adolescent and young adult (AYA) acute leukemia survivors. AYA leukemia survivors had higher mortality rates than the general population that persisted for decades after diagnosis. Male AML survivors had significantly worse survival than females.
Paper Details　
Original Abstract of the Article :
BACKGROUND: There is a growing population of adolescent and young adult (AYA, age 15-39 years) acute leukemia survivors in whom long-term mortality outcomes are largely unknown. METHODS: The current study utilized the Surveillance, Epidemiology, and End Results (SEER) registry to assess long-term o...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/35553621

データ提供：米国国立医学図書館（NLM）

A Long-Term Perspective on Acute Leukemia Survival: A SEER Analysis

The world of [oncology] is constantly evolving, with advances in treatment leading to improved survival rates for many cancers. But what about the long-term health of survivors? This study, published in [journal name], takes a deep dive into the long-term outcomes of adolescent and young adult (AYA) acute leukemia survivors.

Using data from the Surveillance, Epidemiology, and End Results (SEER) registry, the authors analyzed the outcomes of 1,938 AYA acute lymphoblastic leukemia (ALL) and 2,350 AYA acute myeloid leukemia (AML) survivors diagnosed between 1980 and 2009. This study provides a valuable perspective on the long-term health of these survivors.

The findings reveal that while survival rates for AYA leukemia survivors have improved, their mortality rates remain higher than the general population even decades after diagnosis. The study also highlights the impact of factors such as diagnosis age, sex, race/ethnicity, and socioeconomic status on survival.

The Importance of Long-Term Follow-Up: A Lifelong Journey

The study demonstrates the vital importance of long-term follow-up for AYA leukemia survivors. This research underscores the fact that cancer treatment is often just the beginning of a lifelong journey.

Supporting Survivors: A Multifaceted Approach

The results highlight the need for ongoing research into long-term effects and risk factors for mortality in AYA leukemia survivors. This research is an important reminder that cancer survivorship requires a multifaceted approach, involving not only medical care but also social and emotional support.

Dr. Camel's Conclusion

While the desert of cancer treatment may be harsh, this research offers a hopeful oasis. The study's findings underscore the importance of long-term care and ongoing research to improve the quality of life for AYA leukemia survivors. It's a reminder that while treatment is a vital part of the journey, supporting survivors throughout their lives is essential.

Date :
  1. Date Completed 2022-06-02
  2. Date Revised 2022-12-02
Further Info :

Pubmed ID

35553621

DOI: Digital Object Identifier

NIHMS1794755

Related Literature

Article Analysis
・Causes of acute myeloid leukemia (aml)
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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