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Analgesic efficacy and side-effect profile of paracetamol/codeine and paracetamol/dextropropoxyphene after surgical removal of a lower wisdom tooth.

Author: BertilsonS O, HenriksonP A, KahnbergK E, SagneS, ThilanderH

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This trial compared the pain-relieving effects of paracetamol/codeine and paracetamol/dextropropoxyphene in patients undergoing wisdom tooth removal. Paracetamol/codeine provided better pain relief and lasted longer. Side effects were more common in women taking paracetamol/codeine.
Paper Details　
Original Abstract of the Article :
A double-blind randomized analgesic trial was carried out on 180 patients undergoing surgical removal of an impacted lower wisdom tooth. The patients took their first dose of either 1000 mg paracetamol plus 60 mg codeine or 650 mg paracetamol plus 65 mg dextropropoxyphene when pain appeared after th...See full text at original site
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引用元：
https://doi.org/10.1177/030006058701500204

データ提供：米国国立医学図書館（NLM）

Analgesic Efficacy of Paracetamol/Codeine and Paracetamol/Dextropropoxyphene

This double-blind randomized controlled trial compares the analgesic efficacy and side-effect profiles of two common pain relief combinations: paracetamol/codeine and paracetamol/dextropropoxyphene. The study included 180 patients undergoing surgical removal of impacted lower wisdom teeth.

Paracetamol/Codeine's Superior Analgesic Efficacy

The study found that paracetamol/codeine demonstrated superior analgesic efficacy compared to paracetamol/dextropropoxyphene. Patients receiving paracetamol/codeine experienced greater pain relief and longer durations of effect. However, side effects were more frequent in women taking paracetamol/codeine.

Choosing the Right Pain Relief

This research provides valuable insights into the effectiveness of different pain relief medications. The results suggest that paracetamol/codeine may be a more effective option for post-surgical pain management, although side-effect profiles should be considered.

Dr. Camel's Conclusion

Choosing the right pain medication can be a tough decision, like navigating a desert path. This study provides some guidance by comparing the efficacy and side-effect profiles of two common pain relief combinations. It's crucial to consult with your doctor to determine the best course of treatment for your specific needs.

Date :
  1. Date Completed 1987-07-16
  2. Date Revised 2020-12-09
Further Info :

Pubmed ID

3556263

DOI: Digital Object Identifier

10.1177/030006058701500204

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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