Long-term chemoprevention in patients with adenomatous polyposis coli: an observational study.

Author: HaubKatharina, Holinski-FederElke, LanerAndreas, LocherMelanie, MorakMonika, NeuhannTeresa M, Steinke-LangeVerena

Paper Details 
Original Abstract of the Article :
Prospective short-term studies on effectiveness of non-steroidal anti-inflammatory drugs (NSAIDs) point towards a decrease in the number and size of polyps. Effectiveness and safety in the prevention of progression in familial polyposis with NSAIDs in long-term use, which is the prerequisite for the...See full text at original site
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引用元:
https://doi.org/10.1007/s10689-022-00292-2

データ提供:米国国立医学図書館(NLM)

Long-Term Chemoprevention in Patients with Adenomatous Polyposis Coli: An Observational Study

This observational study investigates the long-term effectiveness and safety of sulindac, a non-steroidal anti-inflammatory drug (NSAID), in chemopreventing the progression of adenomatous polyposis coli (APC). The authors analyzed data from 54 patients with APC who underwent long-term sulindac treatment, observing a significant decrease in polyp burden in most patients. The study found that sulindac chemoprevention was effective and safe for long-term management of APC, highlighting its potential as a valuable treatment option for this condition.

Sulindac Chemoprevention: A Promising Strategy for Adenomatous Polyposis Coli

This study provides compelling evidence for the long-term effectiveness and safety of sulindac chemoprevention in patients with APC. The findings suggest that sulindac can significantly reduce polyp burden and may be a valuable tool for managing the progression of this condition. This research offers a promising avenue for long-term management of APC, potentially improving the quality of life for patients.

Harnessing the Power of Chemoprevention: A Journey of Hope

This study underscores the potential of chemoprevention as a powerful strategy for preventing and managing disease. Just as a camel uses its innate instincts to navigate the desert and avoid treacherous terrain, chemoprevention aims to prevent the development or progression of disease. This research offers a glimmer of hope for patients with APC, demonstrating that long-term chemoprevention with sulindac can effectively manage the condition and improve overall health.

Dr. Camel's Conclusion

This observational study provides valuable insights into the long-term effectiveness and safety of sulindac chemoprevention in patients with adenomatous polyposis coli. The findings suggest that sulindac can be an effective and safe treatment option for managing this condition. As a camel who has witnessed the resilience of life in the harsh desert environment, I am inspired by the potential of chemoprevention to prevent and manage disease. This research offers a promising avenue for improving the lives of patients with APC, providing a beacon of hope for those battling this challenging condition.
Date :
  1. Date Completed 2022-11-08
  2. Date Revised 2023-01-06
Further Info :

Pubmed ID

35570229

DOI: Digital Object Identifier

10.1007/s10689-022-00292-2

Related Literature

SNS
PICO Info
in preparation
Languages

English

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