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Side Effects of Chronic Methadone Use in Opioid Addiction: A Scoping Review on Hematological Derangements.

Author: AngWei Chern, AnuarAmalina, JamaluddinRuzita, KhalidKarniza

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This review analyzed the side effects of long-term methadone maintenance therapy (MMT), focusing on hematological derangements. The review found that MMT is associated with immune system hyperactivation, reduced circulating lymphocytes, and increased blood viscosity. These findings highlight the need for further research to find safer alternatives for managing opioid dependence.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Per oral methadone maintenance therapy [MMT] was introduced as part of harm reduction strategy to manage rising numbers of HIV infections caused by intravenous use of illicit drugs. METHOD: We aim to review published articles related to the side effects of long-term methadone therapy, f...See full text at original site
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引用元：
https://doi.org/10.2174/1574886317666220514154931

データ提供：米国国立医学図書館（NLM）

Methadone Maintenance Therapy: A Balancing Act in the Desert of Opioid Addiction

Methadone maintenance therapy (MMT) is a vital tool in the fight against opioid addiction, offering a lifeline for individuals struggling with this complex and often-fatal condition. However, long-term methadone use can have side effects, including hematological derangements. This study explores the hematological side effects of chronic methadone therapy, reviewing published research to identify the potential risks associated with this treatment. The researchers highlight the need for ongoing monitoring and careful management of hematological parameters in patients receiving MMT, ensuring patient safety and well-being.

Navigating the Side Effects: Understanding the Risks of Methadone Therapy

This study sheds light on the potential hematological side effects associated with long-term methadone therapy. The researchers have provided a comprehensive overview of the risks, urging healthcare professionals to carefully monitor patients receiving MMT and take appropriate action to mitigate potential complications.

Optimizing Methadone Therapy: Balancing Benefits and Risks

This research emphasizes the importance of carefully weighing the benefits and risks of MMT. By understanding the potential hematological side effects, healthcare professionals can better manage patient care, ensuring that the benefits of MMT outweigh the risks.

Dr.Camel's Conclusion

This study is a reminder that even effective treatments can come with potential side effects. The findings highlight the importance of careful monitoring and management of hematological parameters in patients receiving MMT, ensuring the safety and well-being of those relying on this essential treatment.

Date :
  1. Date Completed 2023-03-09
  2. Date Revised 2023-03-09
Further Info :

Pubmed ID

35570535

DOI: Digital Object Identifier

10.2174/1574886317666220514154931

Related Literature

Article Analysis
・Side Effects of methadone
SNS
PICO Info
in preparation
Languages

English

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