Paper Details

  1. Home
  2. Paper Details

Molnupiravir and Its Active Form, EIDD-1931, Show Potent Antiviral Activity against Enterovirus Infections In Vitro and In Vivo.

Author: CaoRuiyuan, ChenXingjuan, DaiQingsong, GuoXiaojia, LiWei, LiYuexiang, LiuMiaomiao, WangZhuang, YanYunzheng, YangXiaotong, ZhongWu

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study explores the antiviral potential of molnupiravir (EIDD-2801) and its active form, EIDD-1931, against enteroviruses. EIDD-1931 demonstrated significant antiviral activity against EV-A71 in vitro and protected mice from lethal EV-A71 challenge in vivo. The results suggest that molnupiravir may be a promising drug candidate for treating enterovirus infections.
Paper Details　
Original Abstract of the Article :
Enterovirus infections can cause hand, foot, and mouth disease (HFDM), aseptic meningitis, encephalitis, myocarditis, and acute flaccid myelitis, leading to death of infants and young children. However, no specific antiviral drug is currently available for the treatment of this type of infection. Th...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227765/

データ提供：米国国立医学図書館（NLM）

Molnupiravir: A Potential Weapon Against Enteroviruses

Enterovirus infections can cause a range of debilitating illnesses, including hand, foot, and mouth disease, meningitis, and even death in infants and young children. This research, like a desert expedition seeking a cure for a deadly plague, investigates the potential of a new antiviral drug, molnupiravir, for treating enterovirus infections.

Molnupiravir's Antiviral Activity: A Promising New Treatment

The study demonstrates that both molnupiravir and its active form, EIDD-1931, exhibit broad-spectrum antiviral activity against enteroviruses. This discovery is like finding a rare and valuable oasis in the heart of a vast desert, offering hope for a new treatment option.

Clinical Potential and Future Directions

The research highlights the potential of molnupiravir as a promising drug candidate for treating enterovirus infections. However, like any desert expedition, further research is needed to fully understand the drug's efficacy, safety, and optimal dosage. This research serves as a crucial step in the journey towards finding a cure for these debilitating viral infections.

Dr.Camel's Conclusion

This research represents a significant milestone in the fight against enteroviruses. The discovery of molnupiravir's potent antiviral activity offers hope for a new treatment option for these dangerous infections. Like a desert explorer discovering a hidden water source, this research provides valuable insights and opens up exciting new avenues for further investigation.

Date :
  1. Date Completed 2022-06-27
  2. Date Revised 2022-07-22
Further Info :

Pubmed ID

35746614

DOI: Digital Object Identifier

PMC9227765

Related Literature

Article Analysis
・Effective treatment of acute flaccid myelitis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.