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Use of a single dose of 70mg/kg chloral hydrate as a hypnotic in nuclear magnetic resonance. A prospective study of 3132 cases.

Author: Groizard BotellaM J, Sistac BallarínJ M, Sistac PalacínJ M, Solé GuixesJ

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Oral chloral hydrate at a dose of 70mg/kg remains a suitable sedative for children undergoing magnetic resonance imaging (MRI) lasting no more than one hour. The study found that chloral hydrate provided adequate hemodynamic stability and was associated with a low incidence of side effects, including desaturation, awakening during the test, prolonged sedation, agitated awakening, nausea, and vomiting.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To assess the mean time to hypnosis, hemodynamic stability, and incidence of complications associated with the administration of 70mg/kg oral chloral hydrate in children scheduled for magnetic resonance imaging (MRI). MATERIAL AND METHODS: Prospective study conducted from January 2000 to...See full text at original site
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引用元：
https://doi.org/10.1016/j.redare.2021.03.017

データ提供：米国国立医学図書館（NLM）

Chloral Hydrate for Sedation in MRI: A Safe and Effective Journey Through the Desert of Pediatric Imaging

Magnetic resonance imaging (MRI) is a valuable diagnostic tool in pediatric medicine, but sedation is often required to ensure patient cooperation and accurate imaging. This study investigates the safety and effectiveness of chloral hydrate, a commonly used hypnotic, for sedation in children undergoing MRI. The researchers conducted a prospective study, analyzing the mean time to hypnosis, hemodynamic stability, and incidence of complications in over 3,000 children who underwent MRI under chloral hydrate sedation.

A Safe Haven in the Desert of Pediatric Sedation: Chloral Hydrate's Effectiveness

The study found that chloral hydrate at a dose of 70 mg/kg was effective in inducing hypnosis in children undergoing MRI, with a low incidence of complications. The medication demonstrated adequate hemodynamic stability, with minimal desaturation, awakening during the test, or prolonged sedation. These findings support the continued use of chloral hydrate as a suitable sedative for short-duration MRI procedures in children, offering a reliable and safe option for this challenging population.

Navigating the Desert of Pediatric Imaging: Finding the Right Path

This study underscores the importance of safe and effective sedation strategies for children undergoing MRI. The study's findings provide valuable insights into the use of chloral hydrate, demonstrating its potential as a safe and effective sedative option for this population. As we navigate the desert of pediatric imaging, we must continue to explore and optimize sedation strategies, ensuring the comfort and safety of our youngest patients.

Dr.Camel's Conclusion

This study provides reassuring evidence for the safety and effectiveness of chloral hydrate for sedation in children undergoing MRI. This study serves as a valuable resource for pediatric healthcare professionals, highlighting the potential of chloral hydrate as a safe and effective option for sedating children during MRI procedures.

Date :
  1. Date Completed 2022-07-11
  2. Date Revised 2022-07-11
Further Info :

Pubmed ID

35753930

DOI: Digital Object Identifier

10.1016/j.redare.2021.03.017

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PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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