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Benefits of esmolol in adults with sepsis and septic shock: An updated meta-analysis of randomized controlled trials.

Author: ChenChun, LiuYi, YangJin, YangXiaolei, YangYi, ZhangJing

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.

Overview

This meta-analysis evaluated the efficacy of esmolol for sepsis and septic shock. Esmolol significantly decreased 28-day mortality, heart rate, tumor necrosis factor-a, and troponin I levels. It did not significantly affect other parameters like length of intensive care unit stay or lung injury.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Sepsis affects millions of patients annually, resulting in substantial health and economic burdens globally. The role of esmolol potentially plays in the treatment of sepsis and septic shock in adult patients remains controversial. METHODS: We undertook a systematic search of PubMed, EM...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259117/

データ提供：米国国立医学図書館（NLM）

Esmolol in Sepsis: A Potential Oasis in the Desert of Infection

Sepsis, a life-threatening condition, can be like a raging desert sandstorm, overwhelming the body's defenses. This research investigates the potential benefits of using esmolol, a medication that slows the heart rate, in patients with sepsis.

This research reviews multiple studies examining the use of esmolol in patients with sepsis. The researchers found that esmolol was effective at reducing mortality, heart rate, and inflammatory markers in patients with sepsis. This finding suggests that esmolol may offer a valuable tool for managing sepsis, providing a potential oasis in this challenging condition.

A Promising Path for Sepsis Management

The results of this research offer hope for patients with sepsis. Esmolol may be a valuable tool for managing this life-threatening condition, potentially improving outcomes and reducing the risk of complications. This study emphasizes the importance of exploring new approaches to treating sepsis, just as a camel seeking a safe route across a desert landscape.

Living with Sepsis: What This Means for You

If you or someone you know is struggling with sepsis, it's crucial to seek immediate medical attention. This research highlights the potential benefits of esmolol, but it's vital to consult with a healthcare professional to determine the best course of treatment for your individual needs.

Dr.Camel's Conclusion

Sepsis can be a fierce and unforgiving desert, but research continues to uncover new strategies for managing this condition. This study highlights the potential benefits of esmolol, offering a potential oasis in the fight against sepsis. It's important to work with healthcare professionals to find the best treatment path, ensuring a safe passage across this challenging terrain.

Date :
  1. Date Completed 2022-07-11
  2. Date Revised 2023-01-03
Further Info :

Pubmed ID

35801730

DOI: Digital Object Identifier

PMC9259117

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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