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Interventions for managing medication-related osteonecrosis of the jaw.

Author: Beth-TasdoganNatalie H, HusseinHeba, MayerBenjamin, PeterJens-Uwe, ZolkOliver

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Medication-related osteonecrosis of the jaw (MRONJ) is a serious complication that can occur in some people taking medications for cancer and osteoporosis. This condition involves bone damage in the jaw, leading to significant pain, difficulty eating, and other problems. The risk of MRONJ varies depending on the medication used, the dose, and how long it's taken. This updated review examines MRONJ and its management.
Paper Details　
Original Abstract of the Article :
Medication-related osteonecrosis of the jaw (MRONJ) is a severe adverse reaction experienced by some individuals to certain medicines commonly used in the treatment of cancer and osteoporosis (e.g. bisphosphonates, denosumab, and antiangiogenic agents), and involves the progressive destruction of bo...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309005/

データ提供：米国国立医学図書館（NLM）

Medication-Related Osteonecrosis of the Jaw (MRONJ): A Complex Desert Landscape

MRONJ is a serious complication that can arise as a consequence of certain medications, often used in the treatment of cancer and osteoporosis. It's like a hidden sandstorm in the jawbone, causing progressive bone destruction. The study reviews the current understanding of MRONJ, emphasizing its significant morbidity and challenging treatment. The researchers highlight the need for improved understanding of MRONJ and development of effective interventions.

Navigating the MRONJ Desert: A Need for Better Understanding

This research underscores the importance of early detection and management of MRONJ. The researchers recommend a multidisciplinary approach involving dentists, oncologists, and other healthcare professionals. This collaborative effort is crucial to effectively navigate this challenging landscape. It's like creating an interconnected network of oases, each offering unique resources to support those affected by MRONJ.

Living with MRONJ: A Call for Collaboration and Research

This research serves as a reminder of the importance of understanding the risks and complexities of medication-related complications. It emphasizes the need for ongoing research and development of more effective treatments for MRONJ. This journey through the desert of MRONJ calls for vigilance, collaboration, and a commitment to finding solutions that improve patient outcomes. We must continue to explore new oases of knowledge and treatment strategies, making the journey through this challenging landscape a little easier.

Dr.Camel's Conclusion

This research highlights the challenging nature of MRONJ, emphasizing the need for collaborative efforts to improve treatment strategies and patient care. It's a reminder that even in the harsh desert landscape of medication-related complications, there are opportunities to find new oases of knowledge and solutions. The journey through this desert requires dedication and a commitment to understanding the complexities of MRONJ. We must continue to explore new pathways and solutions, improving the lives of those affected by this debilitating condition.

Date :
  1. Date Completed 2022-07-25
  2. Date Revised 2023-11-07
Further Info :

Pubmed ID

35866376

DOI: Digital Object Identifier

PMC9309005

SNS
PICO Info
in preparation
Languages

English

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