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The Anti-Leukemia Effect of Ascorbic Acid: From the Pro-Oxidant Potential to the Epigenetic Role in Acute Myeloid Leukemia.

Author: AntonelliS, GurnariC, NogueraN I, OttoneT, SilvestriniG, TravagliniS, VosoM T

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Ascorbic acid, also known as Vitamin C, shows potential as a novel anti-leukemia therapy for acute myeloid leukemia (AML) due to its roles in epigenetic regulation, antioxidant cellular response, and other biological processes.
Paper Details　
Original Abstract of the Article :
Data derived from high-throughput sequencing technologies have allowed a deeper understanding of the molecular landscape of Acute Myeloid Leukemia (AML), paving the way for the development of novel therapeutic options, with a higher efficacy and a lower toxicity than conventional chemotherapy. In th...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352950/

データ提供：米国国立医学図書館（NLM）

Ascorbic Acid: A Potential Weapon Against Acute Myeloid Leukemia

This study examines the [anti-leukemia] potential of [ascorbic acid], also known as [vitamin C], in the treatment of [acute myeloid leukemia] (AML). The researchers explore the [mechanisms of action] of [ascorbic acid] in [AML] cells, highlighting its roles in [epigenetic regulation] and [antioxidant activity]. They conclude that [ascorbic acid] shows promise as a [novel therapeutic] agent for [AML], warranting further [clinical trials].

The Power of Vitamin C: A New Hope for AML Treatment

This study unveils the potential of vitamin C as a therapeutic agent for AML, a type of blood cancer. The research delves into the various mechanisms by which vitamin C might combat AML, highlighting its role in epigenetic regulation and antioxidant activity. This promising development could lead to new treatment options for AML patients.

Harnessing the Power of Vitamin C in the Desert of AML

Just as a camel relies on oases to survive in the desert, AML patients seek relief from the harsh realities of their disease. This study suggests that vitamin C, a simple and readily available nutrient, could become a vital oasis in the fight against AML. Its potential to modulate epigenetic pathways and combat oxidative stress offers a glimmer of hope for patients facing this challenging disease.

Dr.Camel's Conclusion

This research provides a compelling case for exploring the therapeutic potential of ascorbic acid in the treatment of AML. Its ability to modulate epigenetic pathways and exhibit antioxidant activity suggests it could be a valuable weapon in the battle against this challenging disease. Further clinical trials are warranted to fully understand the efficacy and safety of ascorbic acid as a novel treatment option for AML patients.
Date :
  1. Date Completed n.d.
  2. Date Revised 2022-08-09
Further Info :

Pubmed ID

35938170

DOI: Digital Object Identifier

PMC9352950

Related Literature

Article Analysis
・Effects of ascorbic acid (vitamin c)
SNS
PICO Info
in preparation
Languages

English

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