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Targeting endoplasmic reticulum stress using natural products in neurological disorders.

Author: AlexiouAthanasios, Chandrika, DeyAbhijit, DuaKamal, JangraAshok, JhaNiraj Kumar, JhaSaurabh Kumar, KumarDeepak, KumarDinesh, OjhaShreesh, RachamallaMahesh, VermaMehak

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Endoplasmic reticulum stress (ERS) plays a significant role in the pathogenesis of various neurological disorders. This review summarizes the literature on natural products that effectively target ERS pathways to provide therapeutic options for neurological diseases like cerebral ischemia, Parkinson's disease, and Alzheimer's disease.
Paper Details　
Original Abstract of the Article :
The primary aim of this review is to summarize the literature on natural products that are effective in the treatment of various neurological disorders by targeting endoplasmic reticulum stress (ERS). Various electronic databases such as SCOPUS, PubMed, Web of Science, and Google Scholar were search...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.neubiorev.2022.104818

データ提供：米国国立医学図書館（NLM）

Harnessing Nature's Power to Combat Neurological Disorders

Endoplasmic reticulum stress (ERS) is a complex cellular process that plays a role in the development of various neurological disorders. This review summarizes the literature on natural products that can effectively target ERS and potentially offer therapeutic options for conditions like cerebral ischemia, Parkinson's disease, and Alzheimer's disease. The authors compiled a comprehensive overview of research focusing on the potential neuroprotective properties of natural products that target ERS signaling pathways.

Natural Products: A Potential Source of Neuroprotection

The review highlights the promising therapeutic potential of natural products in addressing neurological disorders by targeting ERS. These compounds offer a valuable alternative to conventional treatments, potentially providing benefits with fewer side effects. However, further research is needed to fully understand their mechanisms of action and optimize their therapeutic applications.

Exploring the Potential of Nature's Remedies

This review, like a desert oasis brimming with life-giving water, offers hope for those seeking natural remedies for neurological disorders. The researchers, like tireless explorers, have unearthed valuable insights into the potential of natural products to combat these complex conditions. As we delve deeper into the world of natural medicine, we can expect to uncover even more promising solutions for improving health and well-being.

Dr.Camel's Conclusion

This review, like a camel carrying precious resources across a vast desert, provides valuable insights into the potential of natural products to combat neurological disorders. The researchers, like explorers seeking hidden treasures, have uncovered a wealth of knowledge about natural compounds that target ERS. As we continue our journey through the world of natural medicine, we can expect to discover even more potent and effective solutions for addressing the challenges of neurological diseases.

Date :
  1. Date Completed 2022-09-28
  2. Date Revised 2022-10-20
Further Info :

Pubmed ID

35940309

DOI: Digital Object Identifier

10.1016/j.neubiorev.2022.104818

SNS
PICO Info
in preparation
Languages

English

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