Anxiolytic Effect of Carvedilol in Chronic Unpredictable Stress Model.

Author: AlvesAna Paula Negreiros Nunes, FilhoFrancisco Maurício Sales Cysne, LealLuzia Kalyne Almeida Moreira, MacêdoDanielle S, VasconcelosGermana Silva, VasconcelosSilvânia Maria Mendes, da Silva MedeirosIngridy, de AlmeidaJamily Cunha, de AquinoGabriel Ângelo, de SousaCaren Nádia Soares

Paper Details 
Original Abstract of the Article :
Anxiety disorders are the most prevalent psychiatric disorders being also a comorbid state of other diseases. We aimed to evaluate the anxiolytic-like effects of carvedilol (CVD), a drug used to treat high blood pressure and heart failure with potent antioxidant effects, in animals exposed to chroni...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417788/

データ提供:米国国立医学図書館(NLM)

Carvedilol: A Potential Anxiolytic for Chronic Stress

This research explores the vast desert of anxiety disorders, examining the potential anxiolytic effects of carvedilol (CVD), a medication commonly used for high blood pressure and heart failure. The study, conducted in a chronic unpredictable stress (CUS) animal model, investigated the effects of CVD on anxiety-like behavior and immune-inflammatory responses. The researchers found that CVD effectively reversed the anxiolytic-like effects of CUS, suggesting its potential as a novel anxiolytic agent. Furthermore, CVD modulated immune-inflammatory responses, highlighting its potential for addressing the complex interplay between stress, anxiety, and inflammation.

Carvedilol Offers Hope for Managing Chronic Stress and Anxiety

The study, like a camel finding a refreshing oasis in the desert of stress, reveals the potential of carvedilol as an anxiolytic agent. The results demonstrate that CVD effectively reverses the anxiety-like effects of chronic unpredictable stress, offering a potential therapeutic option for managing stress-related anxiety. The study also highlights the importance of considering the interplay between stress, anxiety, and inflammation in developing effective treatment strategies.

Navigating the Desert of Stress and Anxiety with Carvedilol

This research provides valuable insights for those navigating the desert of stress and anxiety. The study suggests that carvedilol, a medication commonly used for heart conditions, may offer a potential solution for managing stress-related anxiety. However, it's crucial to consult with healthcare professionals before considering any new medication, especially for mental health conditions.

Dr. Camel's Conclusion

This study, like a camel seeking a hidden oasis in a desert of stress, explores the potential of carvedilol as an anxiolytic agent. The research reveals that carvedilol effectively reverses the anxiety-like effects of chronic unpredictable stress, suggesting its potential as a novel therapeutic option for managing stress-related anxiety. This study underscores the complex interplay between stress, anxiety, and inflammation, highlighting the importance of a holistic approach to managing these conditions.

Date :
  1. Date Completed 2022-08-30
  2. Date Revised 2022-08-30
Further Info :

Pubmed ID

36035219

DOI: Digital Object Identifier

PMC9417788

Related Literature

SNS
PICO Info
in preparation
Languages

English

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