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Daridorexant for the Treatment of Insomnia.

Author: DownsEvan, KatariaSaurabh, KayeAlan, ParkerKatelyn, RobinsonChristopher L, SupraRajesh, UritsIvan, ViswanathOmar

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This study provides an overview of insomnia, a complex sleep disorder with significant prevalence and impact on individuals' lives. It reviews the various treatment options, including cognitive-behavioral therapy for insomnia (CBT-I) and different classes of pharmacotherapy, highlighting their mechanisms of action and effectiveness.
Paper Details　
Original Abstract of the Article :
Insomnia is a complex sleeping disorder that affects the lives of many individuals worldwide. Insomnia often occurs in the presence of coexisting comorbidities making it a complex disorder that requires a multifactorial approach to therapy. First-line therapy is cognitive-behavioral therapy for inso...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425279/

データ提供：米国国立医学図書館（NLM）

Insomnia: A Complex Sleep Disorder

Insomnia, the inability to fall or stay asleep, plagues millions of people worldwide. This review focuses on a specific class of medication used to treat insomnia - dual orexin receptor antagonists (DORAs) - and introduces a new drug within this class: daridorexant. It explores the various treatment approaches for insomnia and the role of DORAs in managing this complex sleep disorder.

Dual Orexin Receptor Antagonists: A New Frontier in Insomnia Treatment

DORAs target orexin receptors, which play a key role in regulating wakefulness and sleep. This review highlights the potential of DORAs as an effective treatment option for insomnia. It's like finding a new oasis in the desert, offering a refreshing alternative to traditional insomnia treatments.

Navigating Insomnia Treatment: A Personalized Approach

This review emphasizes the importance of a multifactorial approach to insomnia treatment. It stresses the role of cognitive-behavioral therapy for insomnia (CBT-I) as a first-line therapy, alongside pharmacotherapy. It's like a camel caravan traversing a vast desert - we need to use a combination of tools and strategies to reach our destination.

Dr.Camel's Conclusion

This review provides a comprehensive overview of insomnia and its treatment. It introduces daridorexant as a promising new DORA, offering hope for those seeking relief from insomnia. It's like finding a cool, refreshing breeze in the middle of the desert - a welcome respite from the heat of sleeplessness.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-09-28
Further Info :

Pubmed ID

36045942

DOI: Digital Object Identifier

PMC9425279

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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