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Enhanced Uptake and Retention of 0.03% Bimatoprost, 0.5% 5-Fluorouracil, and 5% Minoxidil After 1,550-nm or 1,927-nm Nonablative Laser Pretreatment.

Author: AgronSamantha, FriedmanPaul M, GeronemusRoy G, KondaAdarsh, ParkerCatherine, WangJordan V

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
CommentA short article/note that provides an opinion/perspective/interpretation on a published paper/topic.

Overview

This study examines the increasing popularity of laser pretreatment with cosmeceutical topicals and the potential to optimize treatment protocols by quantifying the permeation of medical topicals.
Paper Details　
Original Abstract of the Article :
Laser pretreatment with cosmeceutical topicals is growing in popularity. However, lasers may also enhance the uptake of medical topicals that treat dermatologic conditions, such as vitiligo, alopecia, and cancerous and precancerous lesions. Permeation of these topicals must be quantified to optimize...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/36054045

データ提供：米国国立医学図書館（NLM）

Laser-Enhanced Topical Delivery: A New Frontier in Dermatologic Treatment

The use of lasers in dermatology is constantly evolving, with new applications emerging to enhance treatment outcomes. This study investigates the potential of non-ablative laser pretreatment to enhance the uptake and retention of cosmeceutical and medical topicals, including bimatoprost, 5-fluorouracil, and minoxidil. The researchers explored the impact of different laser wavelengths on topical penetration, providing valuable insights into the potential of laser-enhanced topical delivery.

Unlocking the Potential of Laser-Enhanced Topical Delivery

The study revealed that non-ablative laser pretreatment with specific wavelengths (1,550 nm or 1,927 nm) significantly enhanced the uptake and retention of the investigated topicals. These findings suggest that laser-enhanced topical delivery could revolutionize dermatologic treatments, potentially improving efficacy and reducing the required dosage of medications. The researchers' findings provide a strong foundation for further investigation into the mechanisms and applications of this promising technology.

The Future of Dermatologic Treatment: Combining Light and Topical Therapies

The study's findings highlight the exciting potential of combining light-based therapies with topical medications to enhance treatment outcomes. This approach could offer numerous advantages, including improved efficacy, reduced dosage requirements, and potentially fewer side effects. Further research is needed to fully explore the applications of laser-enhanced topical delivery in various dermatological conditions, paving the way for a new era of personalized and effective treatments.

Dr.Camel's Conclusion

This study is a testament to the ongoing innovation in dermatology, showcasing the potential of laser-enhanced topical delivery to revolutionize treatment approaches. The findings encourage further exploration of this promising technology, potentially leading to more effective and targeted treatments for a wide range of dermatological conditions.

Date :
  1. Date Completed 2022-09-08
  2. Date Revised 2022-12-09
Further Info :

Pubmed ID

36054045

DOI: Digital Object Identifier

00042728-202209000-00007

Related Literature

Article Analysis
・Effects of bimatoprost topical
SNS
PICO Info
in preparation
Languages

English

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