Oxidized chondroitin sulfate eye drops ameliorate the prognosis of fungal keratitis with anti-inflammatory and antifungal effects.

Author: LinJing, LongXiaojing, PengXudong, TianXue, ZhanLu, ZhangYingxue, ZhaoGuiqiu

Paper Details 
Original Abstract of the Article :
Fungal keratitis (FK) is a refractory ophthalmic disease that can result in vision impairment and even blindness due to the severe fungal invasiveness and excessive inflammatory response. Therefore, antifungal treatment combined with local immunosuppressive therapy is regarded as the most effective ...See full text at original site
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引用元:
https://doi.org/10.1039/d2tb00114d

データ提供:米国国立医学図書館(NLM)

Fighting Fungal Keratitis: Oxidized Chondroitin Sulfate as a New Weapon

The field of ophthalmology faces constant challenges in combatting infections like fungal keratitis, a serious eye infection that can lead to vision loss. This study investigates the potential of oxidized chondroitin sulfate (OCS) as a novel treatment for fungal keratitis. The researchers discovered that OCS possesses both antifungal and anti-inflammatory properties, making it a promising therapeutic agent. The study's findings offer valuable insights into the potential of OCS as a new weapon in the fight against fungal keratitis.

A New Hope for a Refractory Disease: Oxidized Chondroitin Sulfate Emerges

Oxidized chondroitin sulfate (OCS) demonstrated significant antifungal and anti-inflammatory effects, inhibiting the growth of _A. fumigatus_, reducing inflammation, and ultimately improving the prognosis of fungal keratitis in mice. The study suggests that OCS may offer a new therapeutic strategy for this challenging condition. These results are truly remarkable, highlighting the potential of OCS in managing fungal keratitis.

Protecting Your Eyes: Navigating the Sands of Fungal Keratitis

This research offers hope for patients facing fungal keratitis, providing a potential new treatment option with a promising profile. It highlights the importance of continued research and innovation in ophthalmology, where we can find solutions to even the most challenging eye conditions. As a traveler navigates the desert, carefully avoiding obstacles, so too should we take care of our eyes, safeguarding this precious sense from harm.

Dr.Camel's Conclusion

This study shines a light on the potential of oxidized chondroitin sulfate (OCS) as a promising new treatment for fungal keratitis. Its dual action against fungal growth and inflammation makes it a truly remarkable agent. The research offers hope for patients battling this challenging condition, suggesting a potential new avenue for treatment and a brighter future for eye health.

Date :
  1. Date Completed 2022-10-07
  2. Date Revised 2022-11-01
Further Info :

Pubmed ID

36070420

DOI: Digital Object Identifier

10.1039/d2tb00114d

Related Literature

SNS
PICO Info
in preparation
Languages

English

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