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Live Biotherapeutic <i>Lactococcus lactis</i> GEN3013 Enhances Antitumor Efficacy of Cancer Treatment via Modulation of Cancer Progression and Immune System.
Author: JeonByungkwan, KimHyerim, KimSujeong, KimYulha, KimYunjae, LeeSuro, ParkHansoo
Original Abstract of the Article :
The gut microbiota is responsible for differential anticancer drug efficacies by modulating the host immune system and the tumor microenvironment. Interestingly, this differential effect is highly strain-specific. For example, certain strains can directly suppress tumor growth and enhance antitumor ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455052/
データ提供:米国国立医学図書館(NLM)
Lactococcus lactis GEN3013: A Potential New Ally in Cancer Treatment
The intricate relationship between the gut microbiome and cancer remains a topic of intense research. This study investigates the potential of Lactococcus lactis GEN3013, a live biotherapeutic, as a novel approach for enhancing cancer treatment. The researchers discovered that L. lactis GEN3013 exhibited antitumor activity, suppressing tumor growth, inducing cancer cell death, and augmenting the effectiveness of existing cancer therapies.
Lactococcus lactis GEN3013: A Promising New Tool in the Fight Against Cancer
The study's findings suggest that L. lactis GEN3013, with its ability to modulate both the tumor microenvironment and the host immune system, could be a valuable addition to existing cancer treatments. This approach, like finding a hidden oasis in the vast desert of cancer research, offers a promising new avenue for improving patient outcomes.
The Microbiome: A Hidden Oasis in Cancer Treatment
The gut microbiome, a complex ecosystem of trillions of bacteria, is increasingly recognized as a key player in human health, including its potential role in cancer development and treatment. This study underscores the importance of understanding the microbiome's influence on cancer, paving the way for novel therapeutic strategies.
Dr. Camel's Conclusion
This research highlights the potential of Lactococcus lactis GEN3013 as a promising new tool in the fight against cancer. The findings suggest that this live biotherapeutic, with its unique ability to modulate both the tumor microenvironment and the host immune system, could significantly enhance the effectiveness of existing cancer treatments. This study is a testament to the exciting advances being made in understanding the complex interplay between the microbiome, cancer, and the immune system.
Date :
- Date Completed n.d.
- Date Revised 2023-03-28
Further Info :
Related Literature
English
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