Intracranial hemorrhage after a single dose of Yohimbine in a chronic user of clonidine.

Author: FeldmanRyan, HaggertyAdam, HodappBenjamin, TimpeJoshua

Paper Details 
Original Abstract of the Article :
Yohimbine, an alpha-2 adrenoreceptor antagonist found in a variety of supplements, has been historically used to treat libido, erectile dysfunction, xerostomia, and as a weight loss enhancement. Yohimbine toxicity causes a sympathomimetic syndrome as demonstrated by the case below of a female who de...See full text at original site
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引用元:
https://doi.org/10.1016/j.ajem.2022.08.053

データ提供:米国国立医学図書館(NLM)

Yohimbine: A Potential Hazard for Chronic Clonidine Users

Yohimbine, an alpha-2 adrenoreceptor antagonist found in various supplements, has been used for a range of purposes, including libido enhancement and weight loss. This case study investigates the potential risks associated with yohimbine use, specifically focusing on a female patient who experienced intracranial hemorrhage (ICH) after ingesting a single dose of yohimbine while on chronic clonidine treatment. The authors analyze the case, highlighting the potential for serious adverse effects when yohimbine is combined with certain medications. The study's findings underscore the importance of caution and careful consideration of drug interactions, particularly for individuals on chronic medication.

Navigating the Complex Landscape of Drug Interactions

This case study underscores the importance of understanding drug interactions and the potential risks associated with certain medication combinations. The study suggests that yohimbine, like a rogue sandstorm in the desert, can have unpredictable and potentially harmful effects when used in conjunction with other medications. The study's findings highlight the need for careful monitoring and awareness of potential drug interactions, ensuring the safety of those using yohimbine.

The Importance of Patient Safety and Informed Decision-Making

This case study serves as a stark reminder of the potential hazards of drug interactions. It highlights the importance of open communication between patients and healthcare providers, ensuring that individuals are fully informed about potential risks and benefits of medications. Patients should be encouraged to disclose their complete medication history and discuss any concerns or questions with their doctors. Healthcare providers, in turn, should carefully assess potential interactions and tailor treatment plans to minimize risks. By working together, we can prioritize patient safety and make informed decisions about medication use.

Dr. Camel's Conclusion

As a researcher who has navigated the vast and intricate desert of medical knowledge, I find this case study a powerful reminder of the importance of cautious and informed decision-making. Yohimbine, like a hidden dune in the desert, can be unpredictable and potentially dangerous when combined with certain medications. This case underscores the need for vigilance and careful consideration of drug interactions, especially for individuals on chronic medication. Remember, even in the familiar landscape of medical treatments, there are often hidden dangers. Always seek professional guidance and be proactive in managing your medications.

Date :
  1. Date Completed 2022-12-06
  2. Date Revised 2022-12-06
Further Info :

Pubmed ID

36115742

DOI: Digital Object Identifier

10.1016/j.ajem.2022.08.053

Related Literature

SNS
PICO Info
in preparation
Languages

English

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