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No needles needed: All-oral therapy options for relapsed and refractory multiple myeloma.

Author: FranzJoseph, MyrusElizabeth, RichterJoshua, SanchezLarysa

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Oral therapies are increasingly used for relapsed and refractory multiple myeloma. This review summarizes available and investigational oral therapies, including lenalidomide, pomalidomide, and ixazomib, for patients with different treatment histories and disease characteristics. The review also discusses challenges in oral therapy, such as renal insufficiency and cytopenias.
Paper Details　
Original Abstract of the Article :
Immense progress has been made for the treatment of multiple myeloma over the past two decades, with patient outcomes improving dramatically as a result. Patient quality of life, however, is constantly challenged by complications of the disease, side effects of therapy and the overall burden receivi...See full text at original site
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引用元：
https://doi.org/10.1016/j.blre.2022.100993

データ提供：米国国立医学図書館（NLM）

Multiple Myeloma: Oral Therapy Options for Relapsed and Refractory Disease

Multiple myeloma is a type of blood cancer that affects plasma cells. Despite significant advances in treatment, relapsed and refractory multiple myeloma remain a challenge. This article reviews the current and investigational oral therapy options for these patients, emphasizing the benefits of all-oral regimens in terms of convenience and quality of life.

Oral Therapy for Multiple Myeloma: A Convenient and Effective Option

The article highlights the benefits of all-oral regimens in managing relapsed and refractory multiple myeloma. It provides a comprehensive overview of available and investigational oral therapies, organized by the degree of prior treatment. The article also discusses challenges such as renal insufficiency and cytopenias, highlighting strategies for managing these complications.

Navigating the Desert of Multiple Myeloma: Finding Hope in Oral Therapies

This article provides a valuable resource for understanding the current landscape of oral therapy options for multiple myeloma. It emphasizes the importance of personalized treatment approaches, considering factors such as prior drug refractoriness, disease biology, and patient-specific considerations. By staying informed about the latest advancements in oral therapy, patients and healthcare professionals can work together to navigate the challenges of relapsed and refractory multiple myeloma with greater confidence.

Dr.Camel's Conclusion

Multiple myeloma can be a formidable desert of challenges, but research continues to uncover new ways to manage this disease. The advent of oral therapies offers a beacon of hope for patients seeking effective and convenient treatment options. By embracing personalized approaches and staying informed about the latest advancements, we can work together to create a more supportive and empowering environment for those living with multiple myeloma.

Date :
  1. Date Completed 2023-01-27
  2. Date Revised 2023-02-16
Further Info :

Pubmed ID

36137842

DOI: Digital Object Identifier

10.1016/j.blre.2022.100993

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Languages

English

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