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Is Melatonin the "Next Vitamin D"?: A Review of Emerging Science, Clinical Uses, Safety, and Dietary Supplements.
Author: DarleyCatherine, FahoumMona, FrameJames, HenningMelanie, MinichDeanna M, SchulerCorey B
Original Abstract of the Article :
Melatonin has become a popular dietary supplement, most known as a chronobiotic, and for establishing healthy sleep. Research over the last decade into cancer, Alzheimer's disease, multiple sclerosis, fertility, PCOS, and many other conditions, combined with the COVID-19 pandemic, has led to greater...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571539/
データ提供:米国国立医学図書館(NLM)
Melatonin: The Next Vitamin D?
This research delves into the fascinating world of melatonin, a popular dietary supplement known for its role in regulating sleep cycles. The study utilizes a comprehensive review approach to explore melatonin's potential beyond its chronobiotic function. The authors uncover its antioxidant, immune-boosting, and mitochondrial regulatory capabilities, which are particularly relevant in the context of various diseases like cancer, Alzheimer's, and multiple sclerosis. Intriguingly, melatonin's influence on health mirrors that of vitamin D, both acting as hormones and affecting multiple systems through immune modulation and anti-inflammatory actions. The research also explores the potential link between melatonin deficiency and excessive exposure to artificial blue light, akin to the concern over vitamin D deficiency caused by insufficient sunlight exposure. However, with increased melatonin supplement use, concerns about safety, particularly regarding high doses, long-term use, and its impact on specific populations, have arisen. The authors address these concerns by presenting a thorough analysis of melatonin's mechanisms, clinical applications beyond sleep, safety considerations, and dietary supplementation recommendations. This includes a detailed summary of various melatonin formats, dosage, timing, contraindications, and nutrient combinations.
Melatonin's Impact on Health
The research indicates that melatonin's role in health extends far beyond promoting sleep. Its antioxidant, immune-boosting, and mitochondrial regulatory properties suggest its potential in addressing a wide range of health issues. The study also highlights the striking parallels between melatonin and vitamin D, emphasizing their shared influence on the immune system and anti-inflammatory actions. These findings could have significant implications for the treatment and prevention of chronic diseases.
Melatonin: Navigating the Sands of Supplement Use
While melatonin holds immense promise in various health aspects, the study underscores the importance of cautious supplement use, especially concerning high doses and long-term intake. The authors' thorough analysis provides valuable guidance on melatonin supplementation, including dosage recommendations, appropriate timing, and potential contraindications. Understanding these considerations is crucial for optimizing melatonin's benefits while minimizing any potential risks.
Dr. Camel's Conclusion
As a seasoned researcher who has navigated the vast deserts of scientific knowledge, I find this study's exploration of melatonin's diverse health benefits quite enlightening. The similarities between melatonin and vitamin D are particularly intriguing, highlighting the interconnectedness of our biological systems. This research serves as a valuable roadmap for understanding melatonin's potential applications and navigating the complexities of dietary supplementation. Remember, like a camel navigating a desert, it's essential to approach melatonin supplementation with careful consideration and guidance from healthcare professionals.
Date :
- Date Completed 2022-10-17
- Date Revised 2022-10-19
Further Info :
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