Case report: Alpelisib-induced Stevens-Johnson syndrome.

Author: Abou HusseinAhmed Kamel, DesaiAkshay, KurianChristine Jane, RaffertyWilliam

Paper Details 
Original Abstract of the Article :
Alpelisib is a recently approved treatment for hormone receptor-positive, HER2-negative, PIK3CA-mutated advanced breast cancer. It has been associated with alopecia and rash, but there are no documented cases of Stevens-Johnson Syndrome (SJS) associated with this drug. Here, we detail the first case...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554210/

データ提供:米国国立医学図書館(NLM)

Alpelisib and Stevens-Johnson Syndrome: A Rare Case Report

This case report sheds light on a rare adverse effect of alpelisib, a medication used to treat a specific type of breast cancer. Imagine alpelisib as a powerful camel, carrying a valuable cargo of healing properties, but with a slight risk of unexpected side effects. This report details the first documented case of Stevens-Johnson Syndrome (SJS) associated with alpelisib, a severe skin reaction that can resemble a burning desert landscape. While alpelisib is known to cause alopecia (hair loss) and rash, this severe complication has not been previously observed. This discovery serves as a reminder that even with seemingly well-understood medications, unexpected side effects can emerge.

The Importance of Reporting Adverse Reactions

This case report underscores the importance of reporting adverse drug reactions. It's like leaving breadcrumbs in the desert for other travelers to follow, helping them to navigate potential hazards and avoid getting lost. By sharing this information, healthcare professionals can better understand the risks associated with alpelisib and make informed decisions about its use.

Staying Vigilant

This case report highlights the importance of vigilance when it comes to monitoring for potential adverse reactions to medications, no matter how well-established they may be. It's like carefully observing the desert landscape, watching for signs of danger, and reacting accordingly. We must remain aware of the potential for unexpected side effects and report them promptly to ensure the safety of patients.

Dr.Camel's Conclusion

This report, like a beacon in the vast desert, serves as a reminder that even the most effective therapies can have unintended consequences. It emphasizes the importance of careful monitoring and reporting adverse events to ensure patient safety. It's like having a watchful camel guide, ready to alert us to potential dangers and steer us towards a safe journey.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-10-19
Further Info :

Pubmed ID

36249040

DOI: Digital Object Identifier

PMC9554210

Related Literature

SNS
PICO Info
in preparation
Languages

English

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