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Kefir peptides ameliorate osteoporosis in AKR1A1 knockout mice with vitamin C deficiency by promoting osteoblastogenesis and inhibiting osteoclastogenesis.
Author: ChangGary Ro-Lin, ChenChuan-Mu, ChenWei, CidemAbdulkadir, FanHueng-Chuen, LinWei-Yu, LiuYu-Hsien, TuMin-Yu, YenChih-Ching
Original Abstract of the Article :
The AKR1A1 protein is a member of the aldo-keto reductase superfamily that catalyzes the transformation of D-glucuronate to L-gulonate in the synthesis of L-ascorbic acid (vitamin C, Vit C). We previously demonstrated that AKR1A1 knockout mice (AKR1A1<sup>eGFP/eGFP</sup>) with Vit C deficiency exhib...See full text at original site
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引用元：
https://doi.org/10.1016/j.biopha.2022.113859
データ提供：米国国立医学図書館（NLM）
Kefir Peptides for Osteoporosis in Vitamin C Deficient Mice
[Osteoporosis], a condition characterized by [weakened bones], is a significant public health concern. This study explored the potential of [kefir peptides (KPs)] for treating osteoporosis in [AKR1A1 knockout mice with vitamin C deficiency]. The researchers investigated the effects of KPs on [bone remodeling], specifically by examining their impact on [osteoblastogenesis and osteoclastogenesis] to understand their [osteoprotective] properties.
Kefir Peptides Show Promise for Bone Health
This study explored the potential of [kefir peptides (KPs)] as a natural remedy for [osteoporosis]. The results indicated that KPs significantly improved [bone mineral density] and other bone parameters in [AKR1A1 knockout mice] with [vitamin C deficiency]. Furthermore, KPs were found to promote [osteoblast differentiation] and inhibit [osteoclast differentiation], suggesting a dual effect of KPs in promoting bone formation and reducing bone resorption.
Strengthening Your Bones with Kefir Peptides
The study sheds light on the potential benefits of [kefir peptides] for bone health. While further research is needed to confirm these findings in humans, the results suggest that KPs may have a positive impact on [bone remodeling]. It's important to note that while [kefir peptides] may hold promise, it's crucial to consult with a healthcare professional to discuss appropriate dietary strategies and supplements that address your individual needs.
Dr.Camel's Conclusion
This study offers a glimpse into the potential of [kefir peptides] as a [natural solution] for [bone health]. The findings suggest that KPs may play a beneficial role in [bone remodeling] by promoting [osteoblastogenesis] and inhibiting [osteoclastogenesis]. While further research is needed to fully understand the mechanisms and long-term effects of KPs in humans, this study provides a promising avenue for exploration in the fight against osteoporosis.
Date :
- Date Completed 2022-11-22
- Date Revised 2022-11-22
Further Info :
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