Venetoclax-induced vitiligo in a patient with chronic lymphocytic leukemia.

Author: AbdeenMuath, AsawaPalash, FeltonKiley, KhanCyrus, ListerJohn, RinchuseDerek, SamhouriYazan, VusqaUrwat Til

Paper Details 
Original Abstract of the Article :
Venetoclax, a highly selective Bcl-2 inhibitor, is an orally bioavailable drug that has been approved as first-line therapy for chronic lymphocytic leukemia (CLL) in combination with obinutuzumab, as well as monotherapy in the setting of relapsed CLL. Although some of its life-threatening side effec...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/36255070

データ提供:米国国立医学図書館(NLM)

Venetoclax: A Promising but Potentially Complex Treatment

Venetoclax, a Bcl-2 inhibitor, is a novel drug showing significant promise in the treatment of chronic lymphocytic leukemia (CLL). This research explores the potential of venetoclax as a first-line therapy for CLL. While the study highlights the drug's effectiveness in treating CLL, it also discusses the potential side effects, including vitiligo, a condition characterized by the loss of skin pigmentation.

Navigating the Side Effects of Venetoclax

The study presents a case of venetoclax-induced vitiligo, suggesting that this side effect, while rare, may occur in some patients. The authors emphasize the importance of close monitoring for this and other potential side effects of venetoclax. While vitiligo is not life-threatening, it can be a source of psychological distress for patients. This underscores the need for open communication between patients and healthcare providers regarding any changes in their health.

Understanding the Complexities of Cancer Treatment

Cancer treatment is a complex journey that requires careful consideration of both benefits and risks. While new therapies like venetoclax offer exciting possibilities for improved outcomes, it's essential to understand the potential side effects and work closely with your healthcare provider to manage any challenges that arise. With careful monitoring and a collaborative approach, you can navigate the path towards a healthier future.

Dr.Camel's Conclusion

The development of venetoclax represents a significant advance in the treatment of CLL. This research, however, highlights the importance of recognizing and managing potential side effects. Like a camel navigating a treacherous desert, it's crucial to be aware of potential challenges and have a plan in place to address them. By working together, healthcare professionals and patients can harness the power of venetoclax while mitigating its potential risks.

Date :
  1. Date Completed 2022-10-19
  2. Date Revised 2022-12-16
Further Info :

Pubmed ID

36255070

DOI: Digital Object Identifier

00001813-202211000-00022

Related Literature

SNS
PICO Info
in preparation
Languages

English

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