Efficacy and safety of apremilast in patients with limited skin involvement, plaque psoriasis in special areas and impaired quality of life: Results from the EMBRACE randomized trial.

Author: AugustinMatthias, BarkerJonathan, ConradCurdin, FlowerAndrea, GisondiPaolo, JardonShauna, JullienDenis, MrowietzUlrich, ParisMaria, PicardHernan, ReddyJyotsna

Paper Details 
Original Abstract of the Article :
INTRODUCTION/BACKGROUND: Manifestations of psoriasis in special areas are difficult to treat and are associated with a high disease burden and significant quality of life (QoL) impairment. Topical therapies may be inadequate for these patients, necessitating systemic treatment. OBJECTIVE: The objec...See full text at original site
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引用元:
https://doi.org/10.1111/jdv.18689

データ提供:米国国立医学図書館(NLM)

Apremilast: A Beacon of Hope for Psoriasis in Difficult-to-Treat Areas

Psoriasis, a chronic inflammatory skin condition, can be particularly challenging to manage when it affects certain areas like the scalp, nails, and genitals. This study investigates the efficacy and safety of apremilast, a medication that targets the immune system, in patients with plaque psoriasis in these difficult-to-treat areas. The researchers conducted a randomized controlled trial, comparing apremilast to a placebo, and found that apremilast significantly improved quality of life, skin clearance, and itch relief in patients with psoriasis in special areas.

Apremilast Shows Significant Improvement for Psoriasis in Special Areas

The results demonstrate that apremilast is a promising treatment option for patients with psoriasis affecting special areas. The study found a significant improvement in both quality of life and skin symptoms, suggesting that apremilast can effectively manage psoriasis in these challenging locations.

Living with Psoriasis: A Guide for Patients

If you are struggling with psoriasis, it's important to consult with a dermatologist to discuss the best treatment options for your specific needs. Apremilast may be a valuable addition to your treatment plan, especially if you have psoriasis in special areas. It's a reminder that there is hope for managing psoriasis and living a comfortable life, despite the challenges this condition can pose.

Dr. Camel's Conclusion

Psoriasis can feel like a relentless desert wind, leaving a trail of irritation and discomfort. Apremilast offers a welcome breeze, providing relief for those with psoriasis in difficult-to-treat areas. This study shows that innovative treatments are emerging to help manage this condition, bringing a sense of calm and hope to those living with psoriasis.

Date :
  1. Date Completed 2023-01-17
  2. Date Revised 2023-01-17
Further Info :

Pubmed ID

36300769

DOI: Digital Object Identifier

10.1111/jdv.18689

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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